A Study on Oral Cancer and Its Correlation with Tobacco Chewing, Smoking and Alcohol Drinking In Western Rajasthan

Title: A Study on Oral Cancer and Its Correlation with Tobacco Chewing, Smoking and Alcohol Drinking In Western Rajasthan

Authors: Sunita Soni, Kusum Vaishnav, Ajmal S Bhayal, Ramesh C Purohit, Ashwini Soni

DOI: http://dx.doi.org/10.18535/jmscr/v4i4.38

Abstract

References

Corresponding Author

Abstract

An estimated 300373 new cases and 145353 deaths from lip and oral cavity cancer occurred in 2012 worldwide1. To assess the effect of tobacco chewing, smoking and alcohol drinking in the development of the oral cancer and to determine the interaction among these habits, we conducted a hospital based study in Jodhpur, western Rajasthan. Histopathologically confirmed 100 cases of oral cancer were included in this study. The male to female ratio was 2.70:1. The mean age of oral cancer was found to be 51.15 years. The tongue was the most frequently involved site. In our study oral cancer was significantly associated with tobacco chewing, smoking and alcohol drinking. Patients who had combined habit developed oral cancer earlier than who had habit of tobacco chewing alone or smoking alone. Majority of female patients who had tobacco chewing habit developed oral cancer earlier than male patients. The habit of tobacco chewing alone was found to be significant in cancer of buccal mucosa (BM) and anterior 2/3rd of tongue (AOT) in male patients. In female patients tobacco chewing was not found to have a significant association with oral cancer at all sites. Oral hygiene significantly associated with oral cancer in both gender.

Keywords: Oral cancer, tobacco, smoking, alcohol

References

1. Ferlay J, Soerjomataram I, Ervik M, et al; International agency for research on cancer. Globocan 2012: Estimated cancer incidence, mortality and prevalence worldwide in 2012.

2. Petersen PE. The World Oral Health Report 2003: Continuous improvement of oral health in the 21st century –the approach of the WHO Global Oral Health Programme. Community Dent Oral Epidemiol 2003; 31: 3–23.

3. V. L. Allgar and R. D. Neal. Sociodemographic factors and delays in the diagnosis of six cancers: analysis of data from the “National Survey of NHS Patients: cancer. The British Journal of Cancer 2005; 92(11): 1971-75.

4. Elango, J. K., Sundaram, K. R., Gangadharan, P., Subhas, P., Peter, S., Pulayath, C. and Kuriakose, M. A. Factors affecting oral cancer awareness in a high-risk population in India. Asian Pacific Journal of Cancer Prevention. 2009; 10: 627-30.

5. Ravi Kumar BP, Shankar Reddy Dudala et al An updated Prasad’s socioeconomic status classification for 2013. Int J Res Dev Health 2013; 1(2): 875-78.

6. Sharma P, Saxena S, Aggarwal P . Trends in the epidemiology of oral squamous cell carcinoma in Western UP: An institutional study. Indian J Dent Res 2010; 21: 316-9.

7. Aruna DS, Prasad KV, Shavi GR, Ariga J, Rajesh G, et al. Retrospective study on risk habits among oral cancer patients in Karnataka Cancer Therapy and Research Institute, Hubli, India.Asian Pac J Cancer Prev. 2011;12(6):1561-6.

8. Shenoi R, Devrukhkar V, Chaudhuri, Sharma BK, Sapre SB, Chikhale A. Demographic and clinical profile of oral squamous cell carcinoma patients: A retrospective study Indian J Cancer 2012; 49:21-26.

9. Franceschi S, Bidoli E, Herrero R, et al (2000). Comparison of cancers of the oral cavity, pharynx worldwide: etiological clues. Oral Oncol 2000; 36: 106-15.

10. Bhurgri Y, Bhurgri A, Hussainy AS, et al (2003). Cancer of the oral cavity, pharynx in Karachi -Identification of potential risk factors. Asian Pac J Cancer Prev 2003; 4: 125-30.

11. Kruaysawat W, Aekplakorn W, Chapman RS. Survival time, prognostic factors of oral cancer in Ubon Ratchathani Cancer Center. J Med Assoc Thai 2010; 9: 278-84.

12. Muir C, Weiland L. Upper aerodigestive tract cancers. Cancer 1995; 75:147-53.

13. Subapriya R, Thangavelu A, Mathavan B, Ramachandran CR, Nagini S. Assessment of risk factors for oral squamous cell carcinoma in Chidambaram,Southern India: a case-control study. Eur J Cancer Prev 2007; 16: 251–56.

14. Addala L, Pentapati CK, Thavanati PKR, et al (2012). Risk factor profiles of head, neck cancer patients of Andhra Pradesh, India. Indian J Cancer 2012;49: 215-9.

15. Mathew Iype E, Pandey M, Mathew A, Thomas G, Sebastian P, Krishnan Nair M. Squamous cell carcinoma of the tongue among young Indian adults. Neoplasia 2001; 3:273-7.

16. Vogler WR, Lloyd JW, Milmore BK . A retrospective study of etiological factors in cancer of the mouth pharynx and larynx. Cancer 1962; 13: 246-58.

17. Winn PM, Femonah, Blot J, et al (1981). Snuff dipping and oral cancer among women in the southern United States. N Engl J Med 1981; 304: 745-49.

18. Padmavaty Amma Jayalekshmi, Paleth Gangadharan, Suminori Akiba, Chihaya Koriyama and Raghu Ram K. Nair. Oral cavity cancer risk in relation to tobacco chewing and bidi smoking among men in Karunagappally, Kerala, India: Karunagappally cohort study. Cancer Sci 2011; 102: 460–467.

19. Balaram P, Sridhar H, Rajkumar T, Vaccarella S, Herrero R, Nandakumar A, Ravichandran K, Ramdas K, Sankaranarayanan R, Gajalakshmi V, Munoz N, FranceschiS. Oral cancer in southern India: the influence of smoking, drinking, paan-chewing and oral hygiene .Int J Cancer 2002 Mar 20; 98(3):440-5.

20. Muwonge R, Ramadas K, Sankila R et al. Role of tobacco smoking, chewing and alcohol drinking in the risk of oral cancer in Trivandrum, India: a nested case-control design using incident cancer cases. Oral Oncol 2008; 44(5): 446–54.

21. Rao DN, Desai PB. Risk assessment of tobacco, alcohol and diet in cancers of base tongue and oral tongue --a case control study. Indian J Cancer 1998 Jun;35(2):65-72.

22. Dhar PK, Rao TR, Nair NS, et al . Identification of risk factors for specific subsites within the oral, oropharyngeal region-a study of 647 cancer patients. Indian J Cancer 2000; 37: 114-22.

23. Su C-C, Yang H-F, Huang S-J, et al. Distinctive features of oral cancer in Changhua county: high incidence, buccal mucosa preponderance,, a close relation to betel quid chewing habit. J Formos Med Assoc 2007a; 106, 225-33.

24. Ariyoshi Y, Shimahara M, Omura K, et al. Epidemiological study of malignant tumors in the oral, maxillofacial region: survey of member institutions of the Japanese Society of Oral, Maxillofacial Surgeons, 2002. Int J Clin Oncol 2002; 13: 220-8.

25. Ibayashi H, Pham TM, Fujino Y, et al. Estimation of premature mortality from oral cancer in Japan, 1995-2005. Cancer Epidemiol, 2011; 35: 342-4.

26. Razmpa E, Memari F, Naghibzadeh B (2011). Epidemiologic, clinicopathologic characteristics of tongue cancer in Iranian patients. Acta Med Iran 2011; 49: 44-8.

27. Liu SA, Tsai WC, Wong YK, et al. Nutritional factors, survival of patients with oral cancer. Head, neck 2006; 28: 998-7.

28. Vikrant Ranjan, Sanjay Desai1, Tulika Joshi2, Dewesh Kumar3, Mayank Pancholi1, Raghvendra Singh Yadav. Current trends of carcinoma tongue at a Medical College in Central India: A retrospective study. Clinical cancer investigation journal 2014; 3: 493-96.

29. Agarwal KH, Rajderker SS. Clinico-epidemiological profile of oral cancer: A hospital based study. Indian journal of community health 2012; 24: 80-95.

30. Rao DN, Ganesh B, Rao RS, Desai PB. Risk assessment of tobacco, alcohol and diet in oral cancer--a case-control study. Int J Cancer 1994 Aug 15;58(4):469-73.

31. Datta K, Saha RK, Chakrabarti RN. A simple risk estimates study for oral cavity cancer: practical approach in Indian context. J Indian Med Assoc 1997 Mar; 95(3):70-1.

32. Znaor A, Brennan P, Gajalakshmi V, et al. Independent and combined effects of tobacco smoking, chewing and alcohol drinking on the risk of oral, pharyngeal and esophageal cancers in Indian men Int J Cancer 2003; 105(5):681-6.

33. Rahman M, Sakamoto J, Fukui T. Bidi smoking and oral cancer: a meta-analysis. Int J Cancer 2003; 106(4):600-4.

34. Lin WJ, Jiang RS, Wu SH, et al. Smoking, alcohol,, betel quid, oral cancer: a prospective cohort study. J oncol, 2011, 525976.

Abstract

References

Corresponding Author

Call For Paper Volume 12 Issue 10 November 2024

JMSCR Menu

Impact Factor SJIF 2024: 7.892

Crossref - DOI

Editorial Policy

Frequency of Publication

Submission of Articles

Search