Abstract
A-63-year old male presented with left inguinal swelling. Swelling was non-tender and firm in consistency. It measured 5×3×1 cm. Fine needle aspiration cytology was done. Smears were stained by H&E and Papanicolaou staining methods. Smears were hypercellular and showed plasmacytoid cells. Nucleomegaly and anisonucleosis were seen. Clumped chromatin with single conspicuous nucleolus was also seen. The patient had a recurrent lesion and cytological atypia. Cytological findings suggested the tumour to be a malignant melanoma.
Keywords: Malignant tumour, Groin swelling, Cytoplasmic melanin pigment granules.
References
- Enomoto LM, Levine EA, Shen P, Vetanopoulos KI. Role of Surgery for metastatic melanoma. Surg Clin North Amer 2020; 100: 127-39.
- Gadd MA, Coit DG. Recurrence patterns and outcome in 1019 patients undergoing axillary or inguinal lymphadenectomy for melanoma. Arch Surg 1992; 127:1412-1416.
- Tokita T, Kawahara T, Ito Y, Tsutsumi S, Abe K, Namura K, et al. Primary amelanotic malignant melanoma of the male urethra with inguinal lymph node metastasis successfully controled by nivolumab: A case Urology Case Reports 2018; 18:54-56.
- El-Safadi S, Estel R, Mayser P, Muenstedt K. Primary malignant melanoma of the urethra: a systematic analysis of the current literature. Arch Gynecol Obstet 2014; 289 (5):935-943.
- Eltawansi SA, Panasiti R, Hasanein S. Lourdusamy D, Sharon D. Metastatic malignant melanoma of the inguinal lymph node with unknown primary lesion. Case Reports in Medicine 2015; 2015:879460. doi :10.1155/2015/879460.
- McCarthy SW, Palmer AA, Bale PM, Hirst E. Naevus cells in lymph nodes. Pathology 1974; 6 (4): 351-358.
- Kretschmer L, Neumann C, Preußer K; Marsch WC. Superficial inguinal and radical ilioinguinal lymph node dissection in patients with palpable melanoma metastasis to the groin-An analysis of survival and local recurrence. Acta Oncologica 2001;40:1, 72-78.
- Serpell JW, Carne PWG, Bailey M. Radical lymph node dissection for melanoma. ANZ Journal Surg 2003; 73:294-299.
- Coit DG, Rogatko A, Brennan MF. Prognostic factors in patients with melanoma metastatic to axillary or inguinal lymph nodes. A multivariate analysis. Ann Surg 1991;214(5):627-36.
- Martin BM, Etra JW, Russell MC, Rizzo M, Kooby DA, Staley CA, et al. Oncologic outcomes of patients undergoing videoscopic inguinal lymphadenectomy for metastatic melanoma. J Amer Coll Surgeons 2014; 218:620-626.
- Jakub JW, Lowe M. Howard JH, Farma JM, Sarnaik A, Tuttle T, et al. Oncologic Outcomes of multi-institutional minimally invasive inguinal lymph node dissection for melanoma compared with open inguinal dissection in the second multicenter selective lymphadenectomy trial-11 (MSLT-11). Ann Surgical Oncol 2022; 29: 5910-20.
Corresponding Author
Dr. Ashok Kumar Kapoor
RML Mehrotra Pathology Pvt. Ltd. B-171, Nirala Nagar, Lucknow- 22602, Uttar Pradesh, India
DOI: https://dx.doi.org/10.18535/jmscr/v11i11.04
