Abstract
Introduction: Functional outcome after ischemic stroke is influenced by a variety of factors such as injured brain regions, extend and volume of the infarct. This study aim to correlate the infarct location and functional outcome of the patient.
Materials and Method: This is a Prospective study done at MES Medical College, between December 2020 to June 2022, total 44 patients were admitted and taken MRI with a diagnosis of acute middle circulation ischemic stroke within 48 hours of symptom onset. Location of infarct is correlated with clinical outcome using a modified Rankin score taken at 45 days follow up.
Results: Most of the infarct were located in the right hemisphere. A considerably high impact on functional outcome was found at the insula and surrounding opercular cortex
References
- Bastian Cheng, Nils Daniel Forkert, Melissa Zavaglia, Claus C. Hilgetag, Amir Golsari, Influence of Stroke Infarct Location on Functional Outcome Measured by the Modified Rankin Scale. 29 Apr 2014; 2014;45:1695–1702
- Thom T, Haase N, Rosamond W, Howard VJ, Rumsfeld J, Manolio T et al. Heart Disease and Stroke Statistics—2006 Update A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2006 Feb 14; 113(6):e85–151.
- Pandian JD, Sudhan P. Stroke Epidemiology and Stroke Care Services in India. J Stroke. 2013 Sep; 15(3):128–34.
- Jansen O, Knauth M, Sartor K .Advances in clinical neuroradiology. Akta Neurol.1999; 26:1–7.
- Parsons MW, Barber PA, Chalk J, Darby DG, Rose S, Desmond PM et al .Diffusion and perfusion-weighted MRI response on thrombolysis in stroke.Ann Neurol .2002; 51:28–37.
- Röther J, Schellinger PD, Gass A, Sieber M, Villringer A, Fiebach JB et al. Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke <6 h. Stroke.2002;33:2438–2445.
- Kruetzelmann A, Kohrmann M ,Sobesky J, Cheng B, Rosenkranz M, Rother J et al. Pretreatment Diffusion-Weighted Imaging Lesion Volume Predicts Favorable Outcome After Intravenous Thrombolysis With Tissue-Type Plasminogen Activator in Acute Ischemic Stroke. Stroke. 2011; 42:1251-1254.
- Thijs VN1, Lansberg MG, Beaulieu C, Marks MP, Moseley ME, Albers GW .Is early ischemic lesion volume on diffusion-weighted imaging an independent predictor of stroke outcome? A multivariable analysis. 2000 Nov; 31(11):2597-602.
- Sanak D, Nosal V, Horak D, Bartkova A, Zelenak K, Herzig R et al. Impact of diffusion-weighted MRI-measured initial cerebral infarction volume on clinical outcome in acute stroke patients with middle cerebral artery occlusion treated by thrombolysis.Neuroradiology.2006; 48: 632– 6.
Corresponding Author
Fouz Parween P
DOI: https://dx.doi.org/10.18535/jmscr/v11i10.02
