Abstract
Eosinophilic angiocentric fibrosis is a rare lesion of head and neck region included in the spectrum of Immunoglobulin G4 (IgG4) related disease. It has characteristic histologic findings of onion skin fibrosis and prominent eosinophilia. In the present case, the subject is a 45 year old female presenting with a painless mass in right upper lid of five years duration.
Keywords: Eosinophilic angiocentric fibrosis (EAF) IgG4 related disease conjunctiva.
References
- Heedari HM, Ciotoracu AC, Mitulescu TC, Dimancescu MG, Enache S, Predețeanu D. A clinical case of orbital inflammatory pseudotumor as the primary expression of eosinophilic angiocentric fibrosis. Rom J Ophthalmol. 2021;65(4): 411-8.
- Okuyama S, Yazu H, Ito Y, Minato H, Fujishima H. Eosinophilic Angiocentric Fibrosis in Bilateral Upper Eyelid Conjunctivas: A First Case Report. Am J Case Rep. 2020;21:e924042.
- Holmes DK, Panje WR: Intranasal granuloma faciale. Am J Otolaryngol, 1983; 4(3): 184–6.
- Roberts PF, McCann BG. Eosinophilic angiocentric fibrosis of the upper respiratory tract: a mucosal variant of granuloma faciale? A report of three cases. Histopathology 1985;9:1217-25.
- Onder S, Sungur A. Eosinophilic angiocentric fibrosis: an unusual entity of the sinonasal tract. Arch Pathol Lab Med. 2004;128(1):90–1.
- Deshpande V, Khosroshahi A, Nielsen GP, Hamilos DL, Stone JH. Eosinophilic angiocentric fibrosis is a form of IgG4-related systemic disease. Am J Surg Pathol, 2011; 35(5): 701–6.
- Rothenberg ME. Eosinophilia. N Engl J Med. 1998;338(22):1592–600.
- Altemani AM, Pilch BZ, Sakano E, Altemani JM. Eosinophilic angiocentric fibrosis of the nasal cavity. Mod Pathol. 1997;10(4):391–3.
- Thompson LD, Heffner DK. Sinonasal tract eosinophilic angiocentric fibrosis: a report of three cases. Am J Clin Pathol. 2001;115(2):243–8.
- Okamoto K, Motoishi M, Kaku R, Sawai S, Hanaoka J.A surgical case of eosinophilic angiocentric fibrosis of the lung. Surg Case Rep, 2015; 1(1)
- Leibovitch I, James CL, Wormald PJ, Selva D. Orbital eosinophilic angiocentric fibrosis, A case report and review of literature. Ophthalmology 2006;113:148-52.
- Nguyen DB, Alex JC, Calhoun B. Eosinophilic angiocentric fibrosis in a patient with nasal obstruction. Ear Nose Throat J, 2004; 83(3): 183–4, 186
- Kiratli H, Onder S, Yildiz S, Ozşeker H. Eosinophilic angiocentric fibrosis of the orbit. Clin Exp Ophthalmol, 2008; 36(3): 274–6
- Li Y, Liu H, Han D, Zang H, Wang T, Hu B. Eosinophilic angiocentric fibrosis of the nasal septum. Case Rep Otolaryngol, 2013; 2013: 267285.
Corresponding Author
Vasundhara Sharma
RML Mehrotra Pathology, Nirala Nagar, Lucknow