Abstract
Introduction: Incidence of multiple primaries is increasing on account of exposure to common carcinogen, inherent genetic predisposition and increasing surveillance of cancer survivors.
Materials and Methods: This was a retrospective study of 48 patients with histologically proven double malignancy attending OPD at RCC, Imphal Manipur during a period 2015 to 2019. We had categorized the malignancies as synchronous if the interval between the first and second malignancy was 6 months or less and metachronous if interval was more than 6 months. Cases in whom the possibility of the second malignancy being metastatic deposit from first primary which was not completely ruled out were excluded.
Results: Out of forty-eight dual malignancies twenty-nine were synchronous and nineteen were metachronous. Most common first cancer was head and neck cancer and most common second cancer was gastrointestinal cancers.
Conclusion: Thorough evaluation of patients presenting with a primary malignancy and long-term surveillance of cancer survivors should be emphasized in view of increasing incidence of synchronous and metachronous malignancy.
Keywords: Clinicopathological study, dual malignancy, metachronous, synchronous.
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Corresponding Author
Sunita D. Akoijam
Department of Radiation Oncology, Regional Cancer Centre, RIMS, Imphal, Manipur, India
DOI: https://dx.doi.org/10.18535/jmscr/v9i9.26
