Introduction: Post-Operative Nausea and Vomiting (PONV) is a common and distressing complication after Laparoscopic Cholecystectomy (LC). New guidelines states that cholecystectomy and laparoscopic surgery are associated with high PONV incidence.

Methodology: 60 patients belonging to ASA I and II posted for laparoscopic cholecystectomy were divided into two groups. Group A were preloaded with 500 ml Ringer’s lactate solution, and Group B with 500 ml 5% dextrose. The post-operative nausea and vomiting was assessed by Visual Analogue Scoring (VAS) system, and rescue antiemetic medication were given to patients with VAS >2.

 Results: The mean antiemetic consumption in Group A was 2.33 and in Group B was 0.83.

The mean VAS in Group A was 0.175 and in Group B was 0.051 which is comparatively significant after administration of 5% dextrose. No side effects of hyperglycaemia was noted in the study groups. Inj.ondensetrone prescription rate was low in the study group indicating administration of 5% dextrose is a cost-effective method to prevent PONV.

Conclusion: administration of i.v dextrose preoperatively is one of the safest, cost effective and prophylactic treatment for PONV after laparoscopic cholecystectomy.

Keywords: PONV, Laparoscopic Cholecystectomy, VAS.

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Dr P. Vigneswaran

Department of Anaesthesiology, S.P. Medical College and A.G. Hospitals, Bikaner (Rajasthan), India – 334003