Title: A Comparative Clinical Study of Levobupivacaine (0.5%) and Ropivacaine (0.5%) for Supraclaviculer Brachial Plexus Block

Authors: Dr Vikas Kumar Singh, Dr Rakesh Kumar Singh

 DOI: https://dx.doi.org/10.18535/jmscr/v8i7.08

Abstract

Introduction: Brachial plexus block technique has recently become popular as it is cost effective, better postoperative recovery, preserves CNS function, devoid of side effects of laryngoscopy and systemic hemodynamic changes. Present study was undertaken to compare the 0.5% LEVOBUPIVACAINE and 0.5% ROPIVACAINE in terms of onset of action, duration of action and post operative analgesia in supraclavicular brachial plexus block.

Methods: The study was a prospective, randomized, double blind comparative study which includes 40 patients with ASA grade I & II of either sex, between the ages 18 years to 60 years going for upper limb surgery. cases was divided randomly into two groups: Group L: receive Inj. levobupivacaine hydrochloride 0.5% 25cc and Group R: Receive Inj. ropivacaine hydrochloride 0.5% 25cc. Each individual was allocated to respective group by computer generated randomization chart. The onset of sensory & motor block, duration of action and duration of post operative analgesia were recorded and compare for both groups.

Results: In present study it is observed that the onset of sensory blockade ( p= 0.56 ) & motor blockade (p= 0.54) was comparable in both the groups with prolong duration of sensory & motor blockade (p= 0.000 ) in group L as compare to group R. The time for first rescue analgesia required post operatively was longer in group L as compare to group R  and the difference is significant ( p=0.000 ).  The systolic blood pressure,  diastolic blood pressure & heart rate were comparable in both the groups.

Conclusion: The onset of sensory and motor blockade was comparable in both drugs with prolong duration of action and requires lesser dose of resque analgesic in 0.5% levobupivacaine as compare to 0.5% ropivacaine in supraclavicular brachial plexus block.

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