Title: Evaluation of Endometrial Thickness in Females with Post Menopausal Bleeding
Authors: Dr Chetna Dhamija, Dr CL Thukral
DOI: https://dx.doi.org/10.18535/jmscr/v8i5.69
Abstract
The study evaluated the endometrial thickness in post menopausal bleeding subjects with trans-vaginal /trans-abdominal ultrasonography and further the endometrial thickness was correlated with histopathological findings. This diagnostic study included 50 females who presented with postmenopausal bleeding. All females were subjected to transvaginal ultrasonographic evaluation of the endometrial thickness. These females further underwent dilatation and curettage procedure to obtain endometrial curettings which were subjected to histopathological examination. In the present study 50 females between ages 44 to 68 years were included. Out of the total 50 females who presented with post menopausal bleeding 9 females were diagnosed with endometrial carcinoma, 18 females with endometrial hyperplasia, 16 with benign endometrial glands ,6 with atrophic endometrium and 1 with endometrial polyp on histopathological examination after dilatation and curettage. Mean endometrial thickness was significantly more in cases of malignancy as compared to benign conditions (21.83 vs 11.32 mm; p<0.01). Endometrial thickness was observed to be a significant predictor for malignancy (Area under ROC was 0.844; p-value <0.01) with sensitivity and specificity of 88.9% and 63.4% at a cut-off of 11.7 mm. Although transvaginal sonography endometrial thickness can be used as a screening tool in discriminating normal from abnormal endometrium but cannot differentiate benign from malignant endometrium.
