Abstract

Introduction: Orbital rhabdomyosarcoma (RMS) is a highly malignant tumor that originates mainly from mesenchymal tissue. It is considered a rare and highly aggressive malignancy that should be considered in any orbital which rapidly progresses. Delay in diagnosis and inappropriate treatment negatively affects the outcome.

Case Discussion: 5yr/F presented with LE mass since 4 months associated with globe distortion. h/o trauma 2 years back followed by cataract extraction and secondary IOL implantation with trabeculectomy. 6 months later h/o fall leading to IOL explant, hyphema and vitreous hemorrhage. On examination cavity was filled with mass. CT Scan and MRI Orbit suggestive of Retinoblastoma. Histopathology report following enucleation suggestive of Rhabdomyosarcoma Grade III.

Conclusion: Although rare but it has been postulated that RMS may occur following multiple trauma and since it is one of the few life-threatening diseases that present first to an ophthalmologist; therefore prompt diagnosis and treatment is a life-saving issue.