Abstract
Aim: The aim of this study was to compare the effectiveness of Glycerine Magnesium Sulphate paste vs Heparinoid (Thrombophob) Ointment on Phlebitis among patients on peripheral intravenous therapy.
Background: Pain being the fifth vital sign should not be underestimated. Phlebitis causes pain, and discomfort to patients seeking medical help. Various treatment modalities are available for treating phlebitis.
Design: Quantitative approach, an experimental study with pre-test and post-test design
Methodology: The study was conducted in the general surgical and orthopaedic wards among 110 patients. Block randomization method was used. The subjects were randomly allocated to control and experimental group using Sequentially Numbered, Opaque Sealed envelopes (SNOSE) method. Subjects were observed for 48 hours with an interval of 24 hours. Visual infusion phlebitis scale and numeric pain intensity scale were used to collect data.
Results: Result showed that Glycerine Magnesium Sulphate paste was more effective than Heparinoid (Thrombophob) Ointment application based on the observation at 24 hours (p< 0.0001). The Mean reduction rates in phlebitis at the baseline reading, at 24 hours and at 48 hours is 2.95, 2.67 and 1.78 in the control group and 3.07, 1.51 and 0.55 in the experimental group. Both interventions were found to be effective at 48 hours of the observation.
Conclusion: This study demonstrated evidence on the more effective intervention (Glycerine Magnesium Sulphate paste) for the management of phlebitis.
Trial Registration: The study was registered in Clinical Trials Registry of India (CTRI/2018/05/013888).
Keywords: Pain, Peripheral Intravenous therapy, Phlebitis.
References
- Alexandrou, E., Ray-Barruel, G., Carr, P. J., Frost, S., Inwood, S., Higgins, N., … Rickard, C. M. (2015). International prevalence of the use of peripheral intravenous catheters. Journal of Hospital Medicine, 10(8), 530–533.
- Al, L. P., et. (n.d.). Perception orisk factors for infusion phlebitis among Swedish nurses: a questionnaire study. - PubMed - NCBI. Retrieved May 22, 2018, from https://www.ncbi.nlm.nih.gov/pubmed/14734984
- Curran, E. T., Coia, J. E., Gilmour, H., McNamee, S., & Hood, J. (2000). Multi-centre research surveillance project to reduce infections/phlebitis associated with peripheral vascular catheters. Journal of Hospital Infection, 46(3), 194–202. https://doi.org/10.1053/jhin.2000.0831
- Di Nisio, M., Peinemann, F., Porreca, E., & Rutjes, A. W. (2015). Treatment for superficial infusion thrombophlebitis of the upper extremity. In The Cochrane Library. John Wiley & Sons, Ltd. https://doi.org/10.1002/14651858.CD011015.pub2
- D’souza, B. L. (2016). Effectiveness Magnesium Sulphate Crystal Fomentation Vs Paste Applicationfor Phlebitis among Children Receiving Peripheral Infusion who are Admitted at Selected Hospital at Mangalore, 6, 4.
- Eyk, B. V. (n.d.). Complications of IV Therapy, 10.
- Gallant, P., & Schultz, A. A. (2006). Evaluation of a visual infusion phlebitis scale for determining appropriate discontinuation of peripheral intravenous catheters.
- Huo G, Ying-Jia L, Hui-Juan M.( 2006), Efficacy Observation of Glycerin Magnesium Sulfate Emulsion on the Treatment of Peripheral Phlebitis. Journal of Infusion Nursing; 26: 49-54.
- Hn, R., & D, P. K. (2015). A quasi experimental study to evaluate effectiveness of glycerin magnesium sulphate dressing on phlebitis among patients undergoing peripheral intravenous infusion in selected hospital,vadodara. International Journal of Medical Research & Health Sciences, 4(3), 5–527. https://doi.org/10.5958/2319-5886.2015.00101.0
- (12:26:40 UTC). Introduction to the Visual Infusion Phlebitis (VIP) score. Health & Medicine. Retrieved from https://www.slideshare.net/ivteam/vip-score- introduction
- Jacinto, A. K. de L., Avelar, A. F. M., Wilson, A. M. M. M., Pedreira, M. da L. G., Jacinto, A. K. de L., Avelar, A. F. M., … Pedreira, M. da L. G. (2014). Phlebitis associated with peripheral intravenous catheters in children: study of predisposing factors. Escola Anna Nery, 18(2), 220–226. https://doi.org/10.5935/1414- 8145. 20140032
- Piccini, F., Ragazzoni, G., Valentini, L., Faloia, E., & Gobbi, P. (2014). Intracellular absorption of transdermal magnesium demonstrated by ESEM-EDS. Italian Journal of Anatomy and Embryology, 119(1), 152. https://doi.org/10.13128/IJAE- 15991
- Research on Transdermal Magnesium| Tides Wellness. (2018, January 18). Retrieved May 17, 2018, from https://thetideswellness.com/research-transdermal- magnesium/
- Saini B, Paul P.( 2011). Effectiveness of cold application, heparinoid application and magnesium sulphate application on superficial thrombophlebitis among pateints. Ind J nsg;2(1):4-10
- Taylor, F. (2003). A study of the rates of infection and phlebitis associated with peripheral intravenous therapy at the Royal Hobart Hospital. Australian Infection Control, 8(2), 57–60. https://doi.org/10.1071/HI03057
- Urbanetto, J. de S., Peixoto, C. G., & May, T. A. (2016). Incidence of phlebitis associated with the use of peripheral IV catheter and following catheter removal. Revista Latino-Americana de Enferm-agem, 24. https://doi.org/10.1590/1518-8345.0604.2746
- Uslusoy, E., & Mete, S. (2008). Predisposing factors to phlebitis in patients with peripheral intravenous catheters: A descriptive study. Journal of the American Academy of Nurse Practitioners, 20(4), 172–180. https://doi.org/10.1111/j.1745-7599.2008.00305.x
- Xueming J, Yun L. (2005) Correlative study for managing local tissue damage caused by extravasation of pharmorubicin. Journal of Nurses Training; (1): 329.
- (2013). A Comparative Study to Assess the Effectiveness of Glycerin with Magnesium Sulphate Versus Heparin – Benzyl Nicotinate (Thrombophob) Ointment on Management of Thrombophlebitis among Patients Admitted in Intensive Care Units (ICU) of Selected Hospital In Belgaum, Karnataka, 4(7), 4.
- Zhao Y, Hao Y, Zhang H, Shi J, Xie Y. (2011).Clinical re-evaluation of effects of different treatments to prevent from phlebitis induced by chansu injection. Zhongguo [online] Oct; 36(20):2803-6. Available from: URL: http://www.ncbi.nlm.nih.gov/pubmed/22292370
- Zore, G., & Dias, R. (2012). Effectiveness of Nursing Interventions on Pain Associated with Intramuscular Injection, 3(6), 6
- https://www.researchgate.net/deref/http%3A%2F%2Fdx.doi.org%2F10.21474%2FIJAR01%2F8213.
Corresponding Author
Shaly Selva Grace. E
Professor and Head of Upper GI Surgery Unit, Department of Surgery-Unit -III, Christian Medical College, Vellore