Objectives: The Main aim of the present study is to analyse the spectrum of renal lesions detected on Post mortem.

Material and Method: This was a prospective 3-year study from January 2016 to December 2018 in our department of pathology. The kidneys of post-mortem autopsies performed during these years were subjected to our study. After excluding 14 cases of severely damaged and autolysed tissue, 550 cases of well-preserved renal post-mortem autopsies were included in our study. The stained microscopic sections were examined.

Results: 374 of the 550 autopsies were males, while 186 were females. In 117 (21.27%) cases, the microscopic morphology was close to normal histology. Remaining 433 (78.7%) cases had a nephropathological findings. The percentage of non-glomerular nephropathies (55.04%) was higher as compared to that of glomerular lesions (14.17%).  78 (14.17%) cases exhibited glomerular alterations such glomerular sclerosis and glomerulonephritis. Tubular and interstitial lesions were observed in 180 cases (30.90%) which included acute tubular necrosis, chronic pyelonephritis, tubular haemorrhages and interstitial nephritis. Renal arteriosclerosis was observed in 125 (22.7%) cases. Other lesions such as simple cyst, nephrolithiasis, end stage kidney diseases and cloudy change comprised of 57 cases (0.9%) Renal cell carcinoma was incidentally detected in 3 cases (0.54%).

Conclusion: Our study provided satisfactory information in respect to morphological spectrum of various renal lesions in autopsy.

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Dr Aanchal Khosla

Resident, Department of Pathology, Dr. Shankarrao Chavan Government Medical College, Vishnupuri, Nanded