Background: The uterus is a major female hormone-responsive reproductive organ located in the pelvis. The gross morphology of uterus quite dramatically changes throughout life by changing levels of ovarian hormones. A wide range of diseases, both benign and malignant, involve the uterus and need adequate evaluation on hysterectomy and histopathology.

Aim/Objectives: To identify the different pathological lesions involving the uterus, endometrium and cervix in the hysterectomy specimens.

Material and Methods: This retrospective study was performed in pathology department at tertiary care centre from January 2017 to June 2018. Total 1400 hysterectomy specimens were analyzed for histopathological lesions in uterus, endometrium and cervix.

Results: Majority of the patients were seen in 5^th decade of life. Abnormal Uterine Bleeding was the commonest presenting complaint. Uterine Leiomyoma was the commonest myometrial lesion while chronic cervicitis was the commonest cervical lesion. Normal physiological endometrium was seen in majority of cases. Malignant lesions were seen in 2.1% cases and included squamous cell carcinoma of cervix (18 cases) and adenocarcinoma of endometrium (9 cases). 

Conclusions:  A wide range of lesions are encountered when hysterectomy specimens are subjected to histopathological examination. So it is imperative that every hysterectomy specimen should be subjected to detailed gross and histopathological examination for better postoperative management.

Keywords: Histopathology; Hysterectomy; Cervix; Malignancy.

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Poonam Sharma

Lecturer, Department of Pathology, Government Medical College, Jammu