SYSTEMIC LUPUS ERYTHEMATOSUS is an autoimmune disease assosciated with auto antibody production. The inflammation produced by it can affect and damage many organ systems. The involvement of gastrointestinal system in SLE is well documented. The extent of involvement of git and the frequency of symptoms is being underestimated. Patients present with vague complaints such as abdominal pain, nausea, upper GI bleed with non-specific physical examination findings and inconclusive diagnostic tests and serologic analysis. In SLE diagnosis should be evoked, when clinical picture and endoscopic features are suggestive to present as upper GI bleed like peptic ulcer diease, gastric vascular ectasia

Keywords: SLE,Upper GI bleed, peptic ulcer disease,gastric vascular ectasia.

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Komali Dukka