Abstract
Introduction
Globally breast carcinoma is the leading cause of cancer related death in women worldwide. Despite the high incidence rates, in Western countries, 89% of women diagnosed with breast cancer are still alive 5 years after their diagnosis, which is due to early detection and treatment . The UK and USA have one of the highest incidence rates worldwide (together with the rest of North America and Australia/ NewZealand), making these countries a priority for breast cancer awareness. Estrogen and progesterone and HER-2 protein play a central role in regulating growth kinetics of breast tissue and are powerful predictive markers. now the immunohistochemistry testing for hormonal receptors status is mandatory in breast cancer.
In urban India breast cancer accounts for about 25% to 33% of all cancers in women. In women, incidence rates of breast cancer rise sharply with age until ages 45 to50, when the rise becomes less steep. This change in slope probably reflects the impact of hormonal change (menopause) that occurs about this time. Over 50% breast cancer patients in India present in stages 3 and 4, which will definitely impact their survival and the overall 5 year survival for breast cancer patients in India doesn't appear to be even 60% presently.
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Corresponding Author
Dr Nandini Venkatesh
DOI: https://dx.doi.org/10.18535/jmscr/v7i8.118
