Title: Dengue infections and circulating serotypes in Mizoram-north eastern part of India, from 2016 to 2018
Authors: Dr Lalhmingmawii, Dr RSC Vanlalruati
DOI: https://dx.doi.org/10.18535/jmscr/v7i8.22
Abstract
Objectives: Dengue has emerged as a significant public health problem in Mizoram. In this study, we describe the Dengue fever infections and circulating serotypes for a period of three years from June 2016 to May 2018.
Material and Methods: Two Sentinel Surveillance hospitals in the state of Mizoram, which are the only two Sentinel Surveillance hospitals for Dengue in the whole state were selected for this study. Acute blood samples from each patient suspected of Dengue fever were tested by Dengue specific RT-PCR, NS1 ELISA and IgM ELISA.
Results: Of 2596 febrile cases, 23.72% were NS1 and or RT-PCR positive for Dengue. Dengue serotype 2 was responsible for 87.17% of the cases, Dengue serotype 3 for 7.69% and co-infection of serotype 2&3 in 5.12% of the cases.
Conclusion: DENV-2, and to a lesser extent DENV-3, infection were responsible for a high proportion of febrile illnesses in Mizoram in the years 2016 to 2018.
Keywords: DENV-2, DENV-3, RT-PCR, Serotyping, Mizoram, India.
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