Abstract
Introduction
Steroid cell tumor of the ovary are uncommon sex- cord stromal tumors of ovary with malignant potential. The incidence of steroid cell tumor of the ovary is only 0.1% of all ovarian tumors. There are three subtypes of steroid cell tumor of ovary. These are stroma luteoma, leydig cell tumors and steroid cell tumor NOS. As far as steroid cell tumors, not otherwise specified (NOS) is concerned; it constitutes about 56% of all steroid cell tumors. In literature only a few cases of steroid cell tumors, NOS, have been described. Most of the reported cases described benign cases.
References
- Baloglu A, Bezircioglu I, Cetinkaya B, Karci L, Bicer M. Development of secondary ovarian lesions after hysterectomy without oophorectomy versus unilateral oophorectomy for benign conditions: a retrospective analysis of patients during a nine-year period of observation. Clin Exp Obstet Gynecol. 2010;37:299–302.
- Outwater EK, Wagner BJ, Mannion C, McLarney JK, Kim B. Sex cord-stromal and steroid cell tumours of the ovary. Radiographics. 1998;18(6):1523–46
- Cserepes E, Szucs N, Patkos P, Csapo Z, Molnar F, Toth M, et al. Ovarian steroid cell tumour and a contralateral ovarian thecoma in a postmenopausal woman with severe hyperandrogenism. Gynecol. Endocrinol. 2002;16(3):213–16.
- Liu AX, Sun J, Shao WQ, Jin HM, Song WQ: Steroid cell tumors, not otherwise specified (NOS), in an accessory ovary: a case report and literature review.Gynecol Oncol 2005, 97: 260–262.
- Rubido Valle CD, Fuente de la JLC, Martinez CS, Calvo LN, Escarda MR. Ovarian Steroid Cell Tumour Associated to Endometrial Hyperplasia and Presenting as Postmenopausal Vaginal Bleeding. Gynecol Obstet (Sunnyvale) 2015; 5(9):316.
- Zhao C, Vinh TN, McManus K, Dabbs D, Barner R, Vang R: Identification of the most sensitive and robust immunohistochemical markers in different categories of ovarian sex cord-stromal tumors.Am J Surg Pathol 2009, 33: 354–366.
- Duncan TJ, Lee S, Acheson AG, et al. An ovarian stromal tumor with luteinized cells: an unusual recurrence of an unusual tumor. Int J Gynecol Cancer 2008;18:172–5.
- Hayes MC, Scully RE. Ovarian steroid cell tumors (not otherwise specified). A clinicopathological analysis of 63 cases. Am J Surg Pathol 1987;11:835–45.
- Swain J, Sharma S, Prakash V, Agrawal NK, Singh SK. Steroid cell tumour: a rare cause of hirsutism in a female. Endocrinology, diabetes and metabolism case reports. 2013;2013: 130030.
- Reedy MB, Richards WE, Ueland F, Uy K, Lee EY, Bryant C, van Nagell JR Jr: Ovarian steroid cell tumors, not otherwise specified: a case report and literature review.Gynecol Oncol 1999, 75: 293–297.
Corresponding Author
Dr Shreena Patidar
3rd year Postgraduate Resident, Gujarat Cancer Research Institute (GCRI) Ahmedabad
Address- 6, Jamna Niwas, Opposite Gayatri Dairy, Vitthal Nagar Cross road, Shahibaugh,
Ahmedabad. 380004, India