Abstract
Objective: To assess the safety and efficacy of aortic root enlargement for small aortic root to avoid patient prosthesis mismatch in patients undergoing aortic valve replacement.
Method: We reviewed early outcomes of 4/500 patients who received posterior enlargement of aortic annulus along with AVR from a period of January 2015 to December 2018. All were female patients. St Jude Medical regent valve (SJM) (St Jude Medical, St Paul, Minn) were implanted in 3 patients and Carpentiers-Edwards PERIMOUNT Magna Ease Bioprosthesis (Edwards Life sciences, Irvine, CA, USA) was implanted in one patient. Posterior root enlargement was done by modified manougian technique when the annulus was small for adequately sized valve as per BSA. Patients were followed up with serial echocardiography for a period of mean-17months.
Results: Root enlargement allowed us to implant at least 2 size larger prosthetic valve. There was no mortality. Clamp time was almost doubled. One patient had acute kidney injury in post-operative period. One patient had stuck valve after 3 months. Significant reductions in peak and mean gradients were achieved. Mean reductions in left ventricular dimensions were 12.75%.
Conclusion: Root enlargement done with modified manougian technique is safe and easily reproducible and very useful as a bail out procedure when surgeon encounter a small annulus. Our results favor the continuation of this procedure as it leads to both functional and anatomical improvements of left ventricle.
Keywords: small aortic root, patient prosthesis mismatch, posterior root enlargement.
References
- Nicks R, Cartmill T, Bernstein L. Hypoplasia of the aortic root. The problem of aorticvalve replacement.Thorax 1970;25:339–346.
- Manougian S, Seybold-Epting W. Patch enlargement of the aortic valve ring by extending the aortic incision into the anterior mitral leaflet. J Thorac Cardiovasc Surg 1979;78:402–412.
- Nunez L, Aguado MG, Pinto AG, Larzea JL. Enlargement of the aortic annulus by resecting the commissure between the left and noncoronary cusps. Texas Heart Institute J 1983;10:301–303
- Pibarot P, Dumesnil JG, Cartier PC, Metras J, Lemieux MD.Patient-prosthesis mismatch can be predicted at the time of operation. Ann Thorac Surg 2001;71:S265–8.
- Dumesnil JG, Honos GN, Lemieux M, Beauchemin J.Validation and applications of indexed aortic prosthetic valveareas calculated by Doppler echocardiography. J Am CollCardiol1990;16:637–43.
- Rashtian MY, Stevenson DM, Allen DT, et al. Flow characteristics of bioprosthetic heart valves. Chest 1990;98:365–75.
- Mayumi H, Toshima Y, Kawachi Y, Tokunaga K, Yasui H. Simplified Manouguian's aortic annular enlargement for aortic valve replacement. The Annals of thoracic surgery. 1995 Sep 1;60(3):701-4.
- Bortolotti u, Mossuto e, Maraglino g, Gturaro m, Milano a, livi u, Stellin g, Mazzucco Annular enlargement during aortic valve replacement: preliminary results with a simplified technique. Journal of cardiac surgery. 1992 Sep;7(3):235-9.
- Rahimtoola SH. The problem of valve prosthesis–patient mismatch. Circulation 1978;58:21– 4.
- Blais C, Dumesnil JG, Baillot R, Simard S, Doyle D, Pibarot P. Impact of valve prosthesis-patient mismatch on short-term mortality after aortic valve replacement. Circulation. 2003 26;108(8):983-8.
- Mohty-Echahidi D, Malouf JF, Girard SE, Schaff HV, Grill DE, Enriquez-Sarano ME, Miller FA. Impact of prosthesis-patient mismatch on long-term survival in patients with small St Jude Medical mechanical prostheses in the aortic position. Circulation. 2006 Jan 24;113(3):420-6.
- Pibarot P, Dumesnil JG. Prosthesis-patient mismatch: definition, clinical impact, and prevention. Heart. 2006 Aug 1;92(8):1022-9.
- Svensson LG, Adams DH, Bonow RO, Kouchoukos NT, Miller DC, O'gara PT, Shahian DM,.Schaff HV, Akins CW, Bavaria JE, Blackstone EH. Aortic valve and ascending aorta guidelines for management and quality measures. The Annals of Thoracic Surgery. 2013 Jun 1;95(6):S1-66
- Ruel M, Al-Faleh H, Kulik A, Chan KL, Mesana TG, Burwash IG. Prosthesis–patient mismatch after aortic valve replacement predominantly affects patients with preexisting left ventricular dysfunction: Effect on survival, freedom from heart failure, and left ventricular mass regression. The Journal of Thoracic and Cardiovascular Surgery. 2006 May 1;131(5):1036-44
- Sakamoto Y, Hasimoto K, Okuyama H, Takakura H, Ishii S, Taguchi S, Kagawa H. Prevalence and avoidance of patient prosthesis mismatch in aortic valve replacement in small adults. Ann Thorac Surg 2006;81: 1305–1309
- Castro LJ, Arcidi JM, Fisher AL, Gaudiani VA. Routine enlargement of the small aortic root. A preventive strategy to minimize mismatch. Ann Thoracic Surg 2002;74:31–36.
- Rocha RV, Manlhiot C, Feindel CM, Yau TM, Mueller B, David TE, Ouzounian M. Surgical enlargement of the aortic root does not increase the operative risk of aortic valve replacement. Circulation. 2018 Apr 10;137(15):1585-94.
- Zhong Q, Xiao Y, Chen J, Ma R. Strategy of aortic root enlargement in patients undergoing aortic and mitral valve replacement. The Annals of thoracic surgery. 2010 Sep1;90(3):782-7.
- Urso S, Sadaba R, Aldamiz-Echevarria G. Is patient-prosthesis mismatch an independent risk factor for early and mid-term overall mortality in adult patients undergoing aortic valve replacement. Interactive cardiovascular and thoracic surgery. 2009 Sep 1;9(3):510-8.
Corresponding Author
Dr Anubhav Gupta (Prof and H.O.D.)
Dept of Cardiothoracicvascular Surgery, VMMC and Safderjung Hospital, New Delhi.110049, India