Title: Systemic Manifestations in Aids – Prospective Study in GGH Nalgonda
Authors: Dr C. Yadavendra Reddy MD General Medicine, Dr Pothumudi Srinivasarao MD General Medicine
DOI: https://dx.doi.org/10.18535/jmscr/v7i5.78
Abstract
Background: This study is aimed at surveying the clinical manifestations in GGH nalgonda in patients with aids on art therapy.
Methods: A total of 300 people were selected who came for HIV testing in hospital in the period Dec 2019-Mar 2019. Out of this HIV positive patients were demarcated with cd4 count >=200.a total of 100 cases were selected for this study who were in different age groups.
Results: The distribution of the study showed most of the patients were in the age group of 30-40 years. female incidence more in the study 53%; male incidence around 47%. Most patients presented to the hospital had incidence of anaemia (25%) with cachexia (15%) diarrhea (10%) fever(16%) pneumonia (12%).all these patients were diagnosed as HIV positive through elisa method.
Conclusion: It is observed there is increased incidence of anaemia n patients with HIV along with symptoms pneumonia, cachexia, diarrhea altered haematopoesis occurs in patients with HIV infection. this change affects all three cell lines. consequently HIV infected majority individual suffer from anaemia which is manifested in the study. The cause for these condition are varied and are not fully understood. evidence shows that hiv infects the progenitor cells in the bone marrow, haematopoetic stem cells (hsc) and cause abnormal function(6,7). When hsc’s cannot produce adequate haematopoetic growth factors decreased production occurs(8,9). Also art therapy, opportunistic infections and their treatments can contribute to this problem. further public awareness regarding safe sexual practices can reduce the incidence and further the aids eradication program.
