Title: Microbial Trends and their Antibiotic Sensitivity Pattern In Paediatric and Adult Chronic Suppurative Otitis Media (CSOM), in Tertiary Care Hospital, at Bettiah, West Champaran, Bihar
Authors: Dr Sanjay Kumar, Dr S. N. Singh, Dr Satyendu Sagar
DOI: https://dx.doi.org/10.18535/jmscr/v7i5.31
Abstract
Objective: Chronic Suppurative Otitis Media (CSOM) is one of the commonest illnesses in ENT practice which requires medical attention all the more in children of poor socio-economic status having in past inadequate treatment and negligent medical care. The aim of present study was conducted to evaluate the different aerobic and anaerobic microorganisms causing CSOM in paediatric and adult patients and their antimicrobial susceptibility pattern as a guide to therapy.
Materials and Methods: A total of 126 clinically diagnosed cases of CSOM patients were included in the study. From all the patients 126 samples were collected and processed according to standard CLSI Guidelines.
Results: Out of 90 paediatric CSOM patients, 88 patients (97.77%) were bacterial culture positive while out of 36 adults CSOM patients, 29 patients (80.55%) were culture positive. Bilateral CSOM was slightly more common in adults (28%) than paediatric (23%) age group. It was found that causative organism of CSOM was Polymicrobial in both paediatric (69.18%) and in adult 71.83% of cases while number of organisms isolated per lesion was slightly higher in adults (2.36) as compared to paediatric cases. Staphyloccocus aureus was the commonest aerobic isolates found in paediatric CSOM, while in adult CSOM, Pseudomonas aeruginosa was the commonest one. Among anaerobes Peptostreptococcus spp was commonest in paediatrics CSOM where as Prevotella melaninogenica in adult CSOM. Sensitivity of S. aureus to Doxycycline, Clindamycin, Linezolid were 100%, piperacillin + Tazobacatum 97.8%, cefuroxime was 97.8% while that of gram negative bacilli was higher to ceftriaxone, Azithromycin, Clindamycin, Doxycycline 90 to 100%. Among anarobes higher sensitivity was seen to metronidazole (100%), clindamycin (100%) and ceftriaxone (92%).
Conclusion: In CSOM there was a mixed infection, so that urgent appropriate antibiotic therapy can be given as early as possible to effectively reverse the disease process and thereby preventing long term complications.
Keywords: CSOM, aerobe, anaerobe, Antibiogram.
