Title: An Unusual Case of Gilbert Syndrome –A Case Report
Authors: Harharpreet Kaur, Kiranjit Kaur, Kiran Kumar Singal, Surinder Kumar
DOI: https://dx.doi.org/10.18535/jmscr/v7i5.09
Abstract
Gilbert syndrome is caused by a mutation and deficiency of the conjugating liver enzyme uridine diphosphoglucoronate-glucoronosyltransferase. It is characterized by episodes of mild unconjugated hyperbilirubinemia which is usually less than 3mg/dl .It may pose a diagnostic problem if the level of bilirubin is high as in our case where it was persistently more than 6 mg/dl. However the diagnosis can be established by ruling out other causes of unconjugated hyperbilirubinemia such as haemolysis and vit B12 deficiency. Liver enzymes and ultrasound of abdomen are normal. The patient was typically asymptomatic inspite of deep jaundice. The general practioners need to keep this uncommon cause of jaundice in mind to avoid unnecessary panic and medication as this condition is basically benign and needs only reassurance.
Keywords: Gilbert syndrome; unconjugated hyperbilirubinemia
