Abstract
Introduction: Gestational diabetes mellitus (GDM) is defined as glucose intolerance diagnosed for the first time during pregnancy(1). Indian women have an eleven fold increased risk of developing glucose intolerance during pregnancy compared to Caucasian wome.(20 . Studies suggest there would be a further increase to 20% in incidence rates. Gestational Diabetes not only plays a role in altering the immediate maternal and fetal outcomes but also increases the risk of type 2 diabetes in the future for both mother (A relative risk of 7.43)(3) and the baby(4).
Methods: A cohort study conducted in 202 patients consisting of 101 patients of pregnant women with GDM risk and normal pregnancy each at Department of Paediatrics, Hitech Medical college, Bhubaneswar over a period of 2 years.
Results: Major outcomes included 83(82.2%) women having gestational diabetes had underwent Cesarean Sections and had 4 macrosomic babies. The babies of these mothers also had the most tendencies to develop hyperbilirubinemia and accounted for a total of 19 NICU admissions with 2 stillbirths.
Conclusion: Gestational Diabetes Mellitus is associated with significant maternal and fetal outcomes.
Keywords: Gestational Diabetes Mellitus, Outcome, LSCS, Complications.
References
- World Health Organization and Department of Noncommunicable Disease Surveillance; Definition, diagnosis and classification of diabetes mellitus and its complications. Report of a WHO consultation. Part 1: diagnosis and classification of diabetes mellitus. World Health Organization, Geneva, 1999.
- Dornhorst A, Paterson CM, Nicholls JS, Wadsworth J, Chiu DC, Elkeles RS et al.; High prevalence of gestational diabetes in women from ethnic minority groups. Diabet Med, 1992; 9(9): 820-825.
- Bellamy L, Casas JP, Hingorani AD, Williams D. Type 2 diabetes mellitus after gestational diabetes: A systematic review and meta analysis. 2009; 373:1773–9.
- Clausen TD, Mathiesen ER, Hansen T, Pedersen O, Jensen DM, Lauenborg J. High prevalence of type 2 diabetes and prediabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hypergly-cemia. Diabetes Care. 2008;31:340–346.
- Hunt KJ, Schuller KL; The increasing prevalence of diabetes in pregnancy. ObstetGynecolClin N Am., 2007; 34(2): 173-199.
- Raja MW, Baba TA, Hanga AJ, Bilquees S, Rasheed, Haq IU, et al. A study to estimate the prevalence of gestational diabetes mellites in an urban block of Kashmir valley (North India) Int J Med Sci Public Health. 2014;3:191–5.
- Bhatt AA, Dhore PB, Purandare VB, Sayyad MG, Mandal MK, Unnikrishnan AG. Gestational diabetes mellitus in rural population of Western India-Results of a community survey. Indian J Endocrinol Metab. 2015;19:507–10.
- Seshiah V, Balaji V, Balaji MS, Sanjeevi CB, Green A. Gestational diabetes mellitus in India. J Assoc Physicians India. 2004; 52:707–11.
- American Diabetes Association (2010) Diagnosis and classification of diabetes mellitus. Diabetes Care 33 Suppl 1: S62-69.
- Bellamy L, Casas J, Hingorani A, Williams D. Type 2 diabetes mellitus after gestational diabetes: A systematic review and meta-analysis. 2009; 373 (9677):1773–1779.
- Fareed P, Siraj F, Lone K. Fetomaternal outcome in women with gestational diabetes mellitus. Int J Res Med Sci 2017;5:4151-4
Corresponding Author
Dr Sasmita Devi Agrawal
Professor and Head of the Department, Paediatric, HMCH
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