Title: A comparative study between intravenous propofol and an equipotent dose of thiopentone for the incidence of sore throat after Laryngeal Mask Airway (LMA) insertion
Authors: Subrata Kumar Mandal, Moumita Ghosh Nandi, Shantanu Ghosh, Manoj Kumar Ray
DOI: https://dx.doi.org/10.18535/jmscr/v7i1.157
Abstract
Introduction: The LMA (Laryngeal Mask Airway) is an excellent alternative method offering advantages of endotracheal intubation while avoiding the deleterious effects of succinylcholine. The present study was designed to draw a comparison as to which of the two induction agents, propofol and thiopentone sodium, caused less incidence of post-operative sore throat (POST) after LMA insertion.
Materials and Methods: Three hundred patients of either sex, ASA 1 and 2, aged 18 to 50 years undergoing minor elective surgeries under general anaesthesia were enrolled in this prospective, randomized, double blind study. Following premedication with midazolam (0.04 mg/kg) and fentanyl (1.5 μg/kg), patients were randomly allocated to be induced with propofol 2 mg/kg (group A, n=140) or thiopentone sodium 5 mg/kg (group B, n=140).
Results: The incidence of POST was statistically significantly greater in group B as compared to group A (p<0.05)
Conclusion: Propofol (2mg/kg) is a superior induction agent than thiopentone sodium (5mg/kg) for facilitating LMA insertion with lesser incidence of post-operative sore throat (POST).
Keywords: airway, laryngeal, mask, propofol, thiopentone, post-operative sore throat.
