Abstract
Background: Thyroid nodular lesions are common clinical problems worldwide for which surgical intervention was the treatment of choice in many cases. Thus, it is challenging for the pathologist to distinguish the neoplastic nodule from non neoplastic ones and further, categorize the malignant tumors wherever possible.
Objective: The objective of this study was to cytological evaluation of FNAC based on the Bethesda thyroid FNA classification system in evaluation of thyroid nodules as well as correlate relevant cases them histopathologically.
Materials and Methods: This study was conducted over 3 years. Fine needle aspiration was done by palpation or ultrasound guided, using a fine (25 G) needle, and cytological smears were stained by Giemsa, H&E and Papanicolaou stain. The cytological findings were classified according to the BSRTC.
Results: Of the 154 cases examined, benign lesions were the most common (92.1%), followed by atypia/follicular lesion of undetermined significance (4.5 %),malignant (3.9%), suspicious for follicular neoplasm/follicular neoplasm (3.9%), and suspicious for malignancy (3.1%). Good cyto-histological correlation (94.4%) was observed. Only 4.5% smears were non-diagnostic.
Conclusions: FNAC is a simple, safe and cost-effective diagnostic modality in the investigation of thyroid disease with high specificity and accuracy. Accurately evaluated, it can reduce surgical intervention in many patients. However, histopathological diagnosis of thyroid nodules is still the gold standard for thyroid lesions.
Keywords: thyroid, cytology, cytopathology, TBSRTC, FNAC.
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Corresponding Author
Dr U.C. Dutta
Director, Lab & Blood Bank, Rahman Hospitals Pvt. Ltd. Guwahati, Assam
Former Prof. & HOD, Deptt. Of Pathology, Gauhati Medical College, Guwahati, Assam
DOI: https://dx.doi.org/10.18535/jmscr/v7i1.94
