Title: Evaluation of total antioxidant capacity before & after administration of iron therapy in iron deficient pregnant women
Authors: Dr Lata Rajoria, Dr Manisha Jain, Dr Madhu Patni (Bhat), Dr Seema Gupta, Dr Garima Vyas, Dr Dharminder Sunda
DOI: https://dx.doi.org/10.18535/jmscr/v7i1.82
Abstract
Background: Pregnancy is characterized by dynamic changes in multiple body systems resulting in increased basal oxygen consumption and in changes in energy substrate use by different organs including the fetoplacental unit. The aim of the present study was to assess the markers of oxidative stress and antioxidative enzymes in pregnant anaemic women.
Material & Methods: The present study is being conducted on pregnant women with anemia of mild, moderate and severe degree admitted or outdoor patient in SMS Medical College & Hospital, Jaipur (Obstetrics and Gynaecology Dept.) Total 50 cases are taken out of them some receive oral iron or parental iron therapy. 50 controls are also taken. History is taken in full details regarding age socio economic status, diet, presenting complaints, and obstetric history.
Results: In our study the incidence of anemia is more in 21-25 year that is 54%. The incidence of such cases who has not taken any form of iron during their antenatal period is 60%. There is significant rise in Hb level before therapy and after therapy (p value <0.0001) and average Hb level of cases who have taken oral iron and i/v iron is 9.91 and 9.93. The comparison of TAC between anemia patients (cases) having oral iron v/s i/v iron is not significant (p=0.35).
Conclusion: One should be vigilant while dealing with severe anaemia in puerperal period. Early diagnosis and treatment of maternal anaemia in the antenatal follow up is critical to minimize perinatal complication.
Keywords: Iron therapy, Antioxidant, Pregnancy, Hb level.
