Title: Study the relationship between hs-CRP level and urinary albumin creatinine ratio (UACR) levels
Authors: Kheta Ram Sharma, Vikas, R P Agrawal, Anil Khatri, Ramesh Rathore
DOI: https://dx.doi.org/10.18535/jmscr/v7i1.80
Abstract
Background: C-reactive protein (CRP), an acute phase reactant, is a highly sensitive marker of inflammation. Its level rises dramatically during an inflammatory process. CRP has a long half life, affordability of estimation and stability of its levels with no circadian variation and therefore is one of the best markers of vascular inflammation.
Methods: Hospital based cross-sectional Study was conducted at Department of Medicine, S.P. Medical College, Bikaner on Type 2 diabetes patients reporting to OPD & IPD of Medicine Department.
Results: Mean hs-CRP in UACR group <30 µg/mg was 1.76±1.37 mg/l and in >30 µg/mg it was 6.12±3.36 mg/l and this difference was found statistically highly significant (p<0.001).
Conclusion: We found hs-CRP is high in microalbuminuria group compared to normoalbuminuria group. It was also found in our study that diabetic nephropathy is associated with hs-CRP level.
Keywords: C-reactive protein (CRP), Inflammation, Urinary albumin creatinine ratio (UACR).