Abstract
Background: Acute kidney injury is the sudden impairment of kidney function, resulting in the retention of urea and other nitrogenous waste products normally cleared by the kidney. Main objective of the present study is to compare the urine creatinine and plasma creatinine differential diagnosis of Acute Kidney Injury.
Research Design: Clinical observation and experimental design were done for the purpose of present study.
Method: We are selected in participants for the present study, these consecutive randomly admitted patients in the department of medicine in Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Sample: Total 75 Patients were selected in the present study.
Result: Observation of the result in present study in no-diuretic group, it was found that the urine creatinine /plasma creatinine (UCr/PCr) area of ROC curve is (0.745), standard error (0.079), 95% of confidence interval (0.578-0.87) and the level of significant in p-value (0.5) is 0.0020; while the with-diuretic group of has found the urine creatinine/plasma creatinine area ROC curve is 0.801, standard error (0.072), 95% of confidence interval (0.637-0.913) and the level of significant in p value (0.5) is 0.0001.
Conclusion: Finding of the result concluded that the finding from our study is that Ucr/Pcr was more sensitive but less specific in differentiating prerenal from intrinsic AKI. The sensitivity is more in diuretic exposed group when cutoff value was 43.6364 (p=0.0001). based on these finding it can be good screening test.
Keywords: Urine Creatinine, Plasma Creatinine, Acute Kidney Injury.
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Corresponding Author
Dr. Pooja Agrawal (DNB, Medicine)
Assistant Professor, Lakhiram Agrawal Memorial Govt. Medical College, Raigarh, CG, India
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v7i1.79
