Abstract
Aım: Children who will be sedated for MRI was compared about the propofol and thiopental application.
Materıal and Methods: ASA I-II, 160 cases between 1 month and 8 years old were included. Initial systolicblood pressure (SBP), diastolic blood pressure (SBP), heart rate, oxygen saturation (SPO2) values were recorded. Group I: Propofol 2 mg / kg bolus, Group II: Thiopental sodium 2 mg / kg bolus. The University of Michigan Sedation Scale (UMSS) was used to determine the sedation level. Age, sex, body weight, ASA, MRI region, total amount of drug used were recorded. The technician performing MRI evaluated the quality of the shots with a verbal scoring system ranging from 1 to 3.
Results: The total dose given to the males was 43.6 ± 20 mg and the females were 38.3 ± 18 mg. The difference was not statistically significant (p = 0.944). In terms of processing time, the difference was statistically significant (p = 0.09). UMSS averaged 2.81 in Group I and 2.60 in Group II, with a statistically significant difference between groups (p = 0.003). There was a statistically significant difference between groups in terms of side effects, desaturation, prolonged sedation and nausea and vomiting (p <0.05).
Conclusıon: Because of the minimal side effects and rapid induction, propofol was under the control of anesthesiologist. Unlike our previous literature, it could be used effectively and reliably even in younger infants.
Keywords: sedation, pediatric, MRI.
References
- Malviya S, Voepel-Lewis T, Eldevik OP, Rockwell DT, Wong JH, Tait AR (2000) Sedation and general anaesthesia inchildren undergoing MRI and CT: Adverse events and outcomes. Br J Anaesth 84: 743-8.
- Hubbard AM, Markowitz RI, Kimmel B, Kroger M, Bartko MB (1992) Sedation for pediatric patients undergoing CT and MRI. J Comput Assist Tomogr 1 6: 3-6.
- Peden CJ, Menon DK, Hall AS, Sargentoni J, Whitham JG (1992) Magnetic resonance for the anaesthetist. Anaesthesia 47: 50817.
- Frush DP, Bisset III GS (1995) Sedation of children in radiology: Time to wake up.AJR 165: 913-4.
- Karlýk SJ, Heatherley T, Pavan F, Stein J, Lebrron F (1988) Patient anesthesia and monitoring at 1.5 Tesla MRI installation. Magn ResonMed 7: 210-21.
- Bloomfield EL, Masaryk TJ, Caplin A, Obuchowski NA, Schubert A, Hayden, Ebrahim ZY, Ruggieri PM, Goske MJ, Ross JS (1993) Intravenous sedation for MR imaging of the brain and spine in children: Pentobarbital versus propofol. Radiology 186:93-7.
- American Academy of Pediatrics, American Academy of Pediatric Dentistry, Cote CJ, Wilson S, Work Group on Sedation (2006) Guidelines for monitoring and management of pediatric patients during and after sedation for diagnostic and therapeutic procedures: an update. Pediatrics 118:2587-2602.
- Haslam PJ, Yap B, Mueller PR, Lee MJ (2000) Anaesthesia practice and clinical trends in interventional radiology: a European survey. Cardiovasc Intervent Radiol 23:256-61.
- Derbent A, Oran I, Parildar M, Yurtseven T (2005) Adverse effects of anesthesia in interventional radiology. Diagn Interv Radiol 11:109-12.
- Arlachov Y, Ganatra RH (2012) Sedation/anaesthesia in paediatric radiology. Br J Radiol 85,1018-31.
- Mallory M, Baxter A, Kost S (2009) Propofol vs pentobarbital for sedation of children undergoing magnetic resonance imaging: results from the Pediatric Sedation Research Consortium. Pediatric Anesthesia 19:601-11.
- Adaş C, Adaş H, Ergun G, Aydın N, et al (2013) Comparison of Comfort, Recovery and Discharge Times of Sodium Thiopental and Propofol Anesthesia in Pediatric Patients who Underwent Outpatient Anesthesia for Magnetic Resonance Imaging. J Kartal TR 24(1):1-4 https://doi.org/ 10,5505/jkartaltr.2013,57704.
- Dalal PG, Murray D, Cox T, et al (2006) Sedation andn and Anesthesia Protocols Used for Magnetic Resonance Imaging Studies in Infants: Provider and Pharmacologic Considerations. Anesth Analg 103:863-68.
- Pershad J, Godambe S (2004) Propofol for procedural sedation in the pediatric emergency department. J Emerg Med 27(1):11-4
- Kedareshvara K S., Dhorigol MG, Rajesh M (2016) Comparison of propofol and thiopentone along with ketamine for paediatric MRI sedation. International Journal of Research in Medical Sciences 4(2):381-384
Corresponding Author
Fatih Dogu Geyik, M.D.
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Tel: 90 216 458 30 00 Fax: 90 216 352 00 83
DOI: https://dx.doi.org/10.18535/jmscr/v7i1.74
