Abstract

Hyperuricemia is clinical condition in which Serum uric acid level exceeds 7 mg/dL¹. It is characterised by pain, tenderness and swelling of affected joints. Uric acid metabolism follows different pathways. Uric acid is the end product of purine metabolism. Purins are derived partly from the diets (organ meat, meat extracts, yeast, legumes, fish, beer, mushrooms etc.) and partly from endogenous metabolism. In the liver nucleic acids and purine nucleotides are degraded to form the purine bases xanthine and hypoxanthine². These are oxidised to form uric acid by enzyme xanthine oxidase. The urates circulate in the plasma to be excreted mainly by the kidneys. Increased production of uric acid, reduced urinary elimination or a combination of both these processes lead to hyperuricemia. In the Ayurvedic concept, Rasa, Rakta dhatu dushti and srotodushti due to improper digestion is responsible for the condition. Vibheetaki is a drug described extensively in Ayurvedic classics can correct these conditions at dathu and sroto level. In this study an attempt is made to analyse the efficacy of fruit rind of Vibheetaki in Hyperuricemia and associated conditions

Keywords: Terminalia bellerica (Gaertn.)Roxb, Bhavitha Vibheetaki, Hyperuricemia.