Abstract
Background and Objectives: Diabetes is the most common endocrine disorder and a burdensome chronic disease in the world today. The objective of the study is to assess the Microvascular complication-diabetic nephropathy in patients with type 2 DM with respect to their serum levels of Lp (a).
Methodology: The present one year correlation study was conducted in the Department of Medicine, Navodaya Medical College Hospital and Research Centre, Raichur on 100 patients diagnosed to have type 2 DM, proved by laboratory reports during the period of August 2013 to July 2014. A detailed history, physical examination and laboratory tests were done. Serum lipoprotein (a) levels were measured by randox immunoturbido-metric immunoassay. Fasting blood sugar levels along with other relevant investigations were also done.
Results: The results of the study showed that, Lp (a) values progressively increased as age increased. Diabetic patients with nephropathy had increased levels of Lp (a). The present study indicated that better the glycemic control, lesser the mean Lp (a) levels. Lp (a) levels may be used as a screening or predictive tool for development of Microvascular complication like diabetic nephropathy in Diabetic patients.
Conclusion and Interpretation: Lp (a) may be an independent risk factor for the development of diabetic nephropathy in type 2 diabetes mellitus.
Keywords: Lipoprotein (a); Diabetes mellitus; Nephropathy.
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Corresponding Author
Dr Muralidhar H
Post Graduate, Department of General Medicine, S.S. Institute of Medical Sciences & Research Centre, Davangere, Karnataka, India
DOI: https://dx.doi.org/10.18535/jmscr/v6i9.171
