Abstract
Background: Cardiovascular disease (CVD) is leading cause of morbidity and mortality in patients with CKD. This increased risk of cardiovascular disease may begin during early stage of CKD much before the onset of kidney failure. This high burden of CVD mortality is well illustrated by comparing CVD mortality in the dialysis population to the general population. The mortality due to CVD is 10 to 30 times higher in dialysis patient. Our study aim is to identify echocardiographic changes in patients with chronic kidney disease.
Methods: A total of 50 chronic kidney disease patients admitted to Adichunchanagiri medical college hospital, were included in this study. The patients were evaluated as per the history, general physical examination, systemic examination, blood urea, serum creatinine, urine routine and echocardiography.
Results: In the present study echocardiographic abnormalities were observed in 35 patients (70%). Left ventricular hypertrophy was seen in 24 patients (48%). Regional wall motion abnormalities were seen in 7 patients (14%). LA+LV dilatation was seen in 2 patients (4%). Pericardial effusion was seen in 2 patients (4%).
Conclusions: Left ventricular hypertrophy is the commonest morphological abnormality observed. Left ventricular dysfunction is commonest cardiovascular abnormality detected. Echocardiography is a more sensitive diagnostic procedure to detect left ventricular dysfunction.
Keywords: Cardiovascular Disease, Chronic Kidney Disease, Echocardiography.
References
- Bargman JM, Skorecki K. Chronic kidney disease. In: Harrison’s Principles of internal medicine. 19th ed. Vol 2. New York: McGraw-Hill; 2015. p1811.
- Vhora R, Jain R, Kakrani AL, Manade VV. Study of correlation of analysis of lipid profile with echocardiography in end stage renal diseases. In: Applied Physiology and Anatomy Digest 2016 Jun;1:45-7.
- Foley NR, Pafrey SP, Harnett JD, Kent GM, Martin C, Murray DC, et al. Clinical and echocardiographic disease in patients starting end stage renal disease therapy. Kidney International 1995;47:186-92.
- Ramanan C, Chidambaram N, Periyasamy S. A study of cardiovascular abnormalities in chronic kidney disease using electrocardiogram and 2Dechocardiogram. Int J Modn Res Revs 2005 Oct;3(10):960-3.
- Goornavar SM, Pramila Devi R, Ashoka RM. A study of echocardiographic changes in patients with chronic kidney disease. Medical Innovatica 2015 Jul;4(1):1-5.
- Chafekar DS, Rajani RM, Krishna BA. Left ventricular function in end stage renal disease- Non invasive assessment in patients on hemodialysis. Journal of the Association of Physicians of India 1994;42:216-8.
- Singal KK, Singal N, Gupta P, Chander J, Relan P. Cardiac status in patients of chronic kidney disease: an assessment by non-invasive tools. 2016 Apr; 15(02):207-15.
- Soman SS, Sandberg KR, Borzak S, Hudson MP, Yee J. The independent association of renal dysfunction and arrhythmias in critically ill patients. Chest 2002 Aug;122(2):669-77.
- Laddha M, Sachdeva V, Diggikar PM, Satpathy PK, Kakrani AL. Echocardiographic Assessment of Cardiac Dysfunction in Patients of End Stage Renal Disease on Haemodialysis. Journal of the Association of Physicians of India 2014 Jan;62:28-32.
- Debbarma R, Gope M. Echocardiographic profile in patients under maintenance haemodialysis. IOSR Journal of Pharmacy 2015 Feb;5(2):35-7.
Corresponding Author
Yash Khanvilkar
3rd year Junior Resident, Department of Medicine, Adichunchanagiri Institute of Medical Sciences Balagangadharanatha Nagara, Nagamangala, Mandya-571448, Karnataka, India