Abstract
Introduction: Anemia is a very common complication of chronic kidney disease (CKD) and is associated with a poor cardiac health, cognitive function and an overall quality of life. We aimed to assess the various hematological changes in patients with chronic kidney disease and to assess the correlation between hemoglobin and serum creatinine.
Methodology: The study was conducted for a period of one year during which 60 patients with a diagnosis of CKD, and having a serum creatinine value higher than 1.5 mg/dl were included in our study using a predesigned semi-structured questionnaire, we recorded clinical and laboratory related information of the patients. The patients were classified into stages of CKD using eGFR (Estimated Glomerular Filtration Rate). Spearman’s correlation coefficient was calculated to look for correlation between hemoglobin and serum creatinine.
Results: Majority of the patients (n=34) had serum creatinine between 5.1 and 10 mg/dl and half of all patients had hemoglobin level between 7.1 and 10 mg/dl. Iron Overload was seen in 42 patients, and majority of the patients were in CKD stage 4 and 5. Decreased mean serum iron, transferrin and total iron binding capacity was seen in remaining patients.
Conclusion: Prompt identification and correction of anemia in patients with CKD is recommended. Further detailed studies are required to support the results of our study.
Keywords: Chronic kidney disease,Anemia,Creatinine.
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Corresponding Author
V Eswari
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DOI: https://dx.doi.org/10.18535/jmscr/v6i9.118
