Title: Study of Treatment Outcome in Diabetes Mellitus Patients Receiving Directly Observed Treatment Short course (DOTS) for Pulmonary Tuberculosis in Kanyakumari Government Medical College and Hospital: A Retrospective Study
Authors: Muthu Kumar, Joseph Pratheeban, Balaselvi T
DOI: https://dx.doi.org/10.18535/jmscr/v6i9.24
Abstract
Background: Tuberculosis if untreated, the disease may be fatal within five years in 50%-65% of cases. More than 5.7 million new cases of TB were reported to WHO in 2013.About 95% of cases from developing countries. Multiple studies of tuberculosis treatment show that patients with diabetes mellitus may experience poor outcomes.
Materials and Methodology: The demographic profile of pulmonary tuberculosis patient with diabetes was determined by retrospective study on all cases of pulmonary tuberculosis with diabetes admitted in Kanyakumari Govt medical college and hospital from January 2015 to June 2016 for a period of 18 months.
Results: In this study outof the 101 cases, males were predominant, contributing to 86.8% of the total study population. Females contributed about 15.2%. Out of that, cure rates were achieved in 84.8% and the failure rates contributed to 5%. Among the cured patients around 70% are treated with Insulin for diabetes mellitus.
Conclusion: DM patients have increased incidence of TB and poor outcome like failure and relapse. Butgood glycemic control with insulin give better outcome.
Keywords: HbA1C (glycosylated haemoglobin), DM (Diabetes Mellitus), TB (Tuberculosis), DOTS (Directly Observed Treatment Shortcourse), MDR TB (multidrug resistance Tuberculosis).
