Abstract
Patients with Bipolar disorder have high rates of medical, psychiatric and substance abuse disorders which contribute to self harm, reduced life expectancy and decreased quality of life. Lithium effective treatment was an effective treatment for reducing the risk of suicide in people with mood disorders. Also important is the duration of disorder and number of episodes and associated self harm episodes.
Background: Bipolar disorder comprises of manic, hypomanic and depressive episodes. Bipolar disorder is the 6th leading cause of medical disability worldwide among people 15-44 years of age. Bipolar disorder has been deemed the most expensive behavioural health care diagnosis costing more than twice as much as depression per affected individual. Total costs largely arise from indirect costs and are attributable to lost productivity, in turn arising from absenteeism. Apart from lithium a recent study showed that Interpersonal and Social Rhythm Therapy (IPSRT) delayed Bipolar affective disorder recurrence in adults by stabilizing daily routines and sleep/wake cycles.
Keywords: Bipolar disorder, self harm.
References
- Bipolar affective disorder. In: International statistical classification of diseases and related health problems. tenth revision. 2nd edition. vol. 1: Geneva: World Health Organization; 2004; 313- 314.
- Laxman KE, Lovibond KS, Hassan MK. Impact of bipolar disorder in employed populations. Am J Manag Care 2008;14:757–784.
- Bhandari TR, Puri A, Walia R, Aslam S, Purkayastha Mukherjee M. Relationship between dose, serum concentration and response to lithium prophylaxis in bipolar International Journal of Pharmaceutical Sciences Letters 2014 ;4 (4): 399-402.
- Cipriani A, Hawton K, Stockton S ,Geddes JR. Lithium in the prevention of suicide in mood disorders: updated systematic review and meta-analysis. BMJ 2013; 346-f3464
- Baldessarini RJ, Tondo L. Lithium in psychiatry. Revista De Neuro Psiquiatria 2013 ; 6(4).
- Goldstein TR r,Fersch-Podrat R, Axelson DA et al. Early intervention for adoles-cents at high risk for the development of bipolar disorder: pilot study of interpersonal and social rhythm therapy (IPSRT). Psychotherapy (chic). 2013 Dec 30. [epub ahead of print] pmid:
- Markowitz GS, Radhakrishnan J, Kambham N, Valeri AM et al. Lithium nephrotoxicity: progressive combined glomerular and tubulointerstitial nephr-opathy Journal of theAmerican Society of Nephrology 2000; 11(8):1439 – 1448.
- Joyce PR. Age of onset in bipolar affective disorder and misdiagnosis as schizophrenia. Pychological Medicine 1984; 14(01): 145-149.
- Oquendo MA, Galfalvy H, Russo S, Ellis SP, Grunebaum MF, Burke A, Mann JJ. Prospective study of clinical predictors of suicidal acts after a major depressive episode patients with major depressive disorder or bipolar disorder. Am J Psychiatry 2004; 161(8) : 1433-41.
- Oquendo MA, Waternaux C, Brodsky B et al. Suicidal behavior in bipolar mood disorder: clinical characteristics of attempters and non attempters. Journal of Affective Disorders 2000; 59(2):107–117.
- Atkinson M, Sharon , Zibin S, Chuang H. Characterizing quality of life among patients with chronic mental illness:a critical examination of the self-report methodology. Am J Psychiatry 1997; 154(1): 99 -105.
- Weiss RD, Ostacher MJ, et al. Does recovery from substance use disorder matter in patients with bipolar disorders? J Clin Psychiatry 2005; 66(6):730 -735.
Corresponding Author
Dr Ena Sharma
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DOI: https://dx.doi.org/10.18535/jmscr/v6i6.124
