Abstract
Objective: The present study was undertaken to know the role of vaginal hormonal cytology, endometrial biopsy and endocrinological evaluation in the detection of ovulation and various ovulatory dysfunction.
Material & Method: A total of 34 infertile female patient were studied.
Result: On the basis of cytological finding of 34 patients, 10 patient were found to be ovulatory, 22 patients were anouvlatory (including 5 case of atrophic changes) and 2 patients were inconsistent due to inflammatory changes. Endometrial biopsy showed evidence of ovulation in 11 patients and anovulation in 23 patients. Hormonal evaluation indicated endocrinological disorders in 10 patients which may underline anovulatory infertility. In these patients, results were within normal range in rest 24 patients.
Conclusion: Vaginaland endometrial biopsy showed correlation in respect to ovulation in 91.44 % of the cases.
Keywords: Vaginal cytology, Infertility, Endometrial biopsy, Hormonal analysis.
References
- WHO – recent advices in medically assisted conception: report of a WHO Scientific Group. World HealthOrgn. Tech Rep Ser 1992; 822 : 1 – 111.
- Collins JA – Unexplained infertility. in :keye WR , change RJ, Rebar RW , Soules MR, editors .Infertility : evaluation and treatment . Philadelphia : WB saunders , 1995 : 249-62
- Rein dollar RH Novak M, Tho SP, McDonough P – Adult onset amenorrhea : a study of 262 patients Am J ,. Obstetric Gynecol 1986;155:531-43
- Laufer MR, FloorAE, Parsons KRE, Kuntz KM, Barbiewri RL – Hormone testing in women with adult – onset amenorrhea Gynecol Obstet Invest 1995; 40: 200-3.
- Yen SSc, Jaffe RB, editors – reproductive Endocrinology 4th Philadelphia : WB Saunders , 1999
- Weld GL, Bos Chann HW, Ferin J – Symposium on hormonal cytology . Acta Cytol 1968 ;12:87-127.
- Noyes RW – Uniformity of secretory endometrium: study of multiple sections from 100 uteri removed at operation FertilSteril 1956;7:103-9.
- Herrnstein Mark D, Schust D- Infertility In: Berek JS editor Novak’s Gynecology 12th Philadelphia: Lippincott Williams & wilkins,1996:915-9.
- Engineer AD, Tandon, Sharma S – Correlative study of endometrial biopsy, vaginal cytology and cervical mucus arborization to detect ovulation Obstet Gynaecol India 1968; 18: 96-9.
- Rebar RW –Practical evaluation of hormonal status In : Yen SSC, Jaffe RB , editors Reproductive Endocrinology 3rd ed. Philadelphia: WB Saunders, 1991 : 830-86.
Corresponding Author
Dr Soma Thakur
Tutor, Department of Pathology
Sri Krishna Medical College, Muzaffarpur
DOI: https://dx.doi.org/10.18535/jmscr/v6i6.77
