Title: Association between Serum Sex Hormone Levels in Men with Lower Urinary Tract Symptoms
Authors: Nisha Luhadia, Mustafa Ali, Manish Kumar Gupta
DOI: https://dx.doi.org/10.18535/jmscr/v6i6.25
Abstract
Background: The Lower Urinary Tract Symptoms (LUTS) complex consists of filling or irritative symptoms (Frequency, Urgency, Dysuria, Nocturia, and Odynouria) and voiding or obstructive symptoms (Poor stream, Hesitancy, Terminal dribbling, Incomplete voiding and Overflow incontinence. It affects 15–60% of men aged > 40 years. The prevalence rises markedly with age. Present study was designed to evaluate the association between serum sex hormones in men with LUTS.
Objective: Present study was designed to evaluate the association between serum sex hormones in men with LUTS.
Material and Methods: It was a study of one year duration involving 94 male patients and was carried out in KGMU, Lucknow in the Department of Pathology, presenting at Urology OPD, KGMU, Lucknow with complaints of Lower urinary tract symptoms.
Results: Age of patients ranged from 40 to 79 years. Serum free testosterone values ranged from 0.5 to 34.4 pg/ml. Serum total testosterone levels ranged from 0.70 to 12.68 ng/ml. Serum total estradiol levels ranged from 1.03 to 466.47 pg/ml. Serum dihydrotestosterone values ranged from 222.62 to 3467.29pg/ml.
Conclusion: Significant positive correlation was observed between serum levels of estradiol and LUTS.
Keywords: Lower Urinary Tract Symptoms, sex hormones, nocturia.
