Chronic Kidney disease (CKD) is a slow and progressive loss of kidney function over time regardless of cause. CKD virtually affect the functions of all organ system in our human body. Gastrointestinal symptoms and complications are more common in chronic kidney disease

Aim: To study the Clinical symptoms, frequency and type of upper Gastro intestinal lesions in Chronic Kidney disease.

Materials & Methods: A total number of 80 patients diagnosed as CKD Stage (3-5) admitted in medicine ward and nephrology unit from February 2017 to January 2018 were selected for study. All patients underwent a detailed History, Clinical examination, Renal Function tests, Ultrasound Abdomen and upper GI Endoscopy.

Results: Eighty patients of CKD stage 3-5 were included in study, of which 58 were males and 22 were females. Ages of patient ranged from 11- 80 years while maximum age group was from Fifth decade. Majority of patients were in CKD stage 5 .The predominant symptoms were anorexia, nausea and vomiting. Endoscopically, 86% of patients had one or more upper GI mucosal lesions. Lesions were more frequent in the stomach. Inflammatory lesions were the most common upper GI lesion seen.

Conclusion: Gastrointestinal symptoms are common in CKD patients. Majority of the patients have upper GI mucosal lesions in endoscopy. Recognition of these lesions and prompt management can significiantly reduce the morbidity and mortality in CKD patients.

Keywords: Chronic kidney disease, Endoscopy, Mucosal lesions, Symptoms, stages.

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S. Shankar

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