Abstract
Hypothyroidism is one of the most common hormonal disorders being associated with increased cardiovascular morbidity and mortality. Early detection of diastolic dysfunction of left ventricle by echocardiography helps in timely therapeutic intervention with thyroid hormone supplementation and amelioration of symptoms. The main objective of the present study was aimed at the cardiovascular involvement in hypothyroid patients. The present study was carried out in 64 patients of hypothyroidism who attended to the hospital between September 2013 and September 2014 including both outpatients and inpatients.
Echocardiography showed significant reduction in early diastolic filling (E) with augmented late diastolic filling (A) resulting in decreased E/A ratio suggesting significant diastolic dysfunction. Tissue Doppler imaging showed reduction in peak early diastolic velocity (E1) and raised peak late velocity (A1) with increased E/E1 ration which is again suggestive of diastolic dysfunction. LV diastolic dysfunction was impaired in patients with hypothyroidism. Doppler echocardiography might be considered a reliable method for its assessment & further management.
Keywords: Hypothyroidism, Cardiovascular changes, Echocardiography.
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Corresponding Author
Dr Nirmal Kumar Mohanty
Associate Professor, Deptt. of Cardiology, S.C.B. Medical College, Cuttack, India
DOI: https://dx.doi.org/10.18535/jmscr/v6i3.175
