Introduction: Metabolic syndrome refers to cluster of several cardio metabolic risk factors including abdominal obesity, hyperglycemia, dyslipidemia and elevated blood pressure that likely linked to insulin resistance. Vitamin-D deficiency may be a risk factor of metabolic syndrome.

Objective: This study was performed to evaluate the role of vitamin-D in patients of metabolic syndrome and find out its correlation with different parameters of metabolic syndrome.

Material and Methods: 150 metabolic syndrome patients and 150 controls were recruited. Waist circumferences, blood pressure, vitamin-D and other parameter of metabolic syndrome (serum triglyceride, serum HDL cholesterol and fasting plasma sugar) were measured in blood sample collected between January 2012 and December 2014.

Results: Metabolic syndrome patients had significantly reduced circulated level of 25-hydroxy vitamin-D compared with the controls. It was seen that 60% of the cases were deficient in vitamin-D while only 10 % of the controls were deficient in vitamin D.  Cases had higher mean values of systolic and diastolic blood pressure, fasting blood sugars, triglyceride levels and lower mean HDL cholesterol as compared to the controls.

Conclusion: vitamin-D levels were decreased as the metabolic syndrome patients had more than 3 components of metabolic syndrome and showed inverse relationship with increasing number of components.

Keywords: Metabolic syndrome, vitamin D, vitamin-D  deficiency.

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Dr Rahul Kumar

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Jawahar Lal Nehru Hospital, Ajmer, Rajasthan- 305001

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