Abstract
Background: Dengue, a mosquito borne viral infection, caused by a positive stranded RNA (Ribonucleic Acid) virus of the Flaviviridae family with four distinct serotypes (Dengue Virus 1 to 4) is a major cause of morbidity throughout the tropical and subtropical regions of the world.
Objective: The study was aimed at determining the prevalence of the disease in Mumbai, Maharashtra.
Materials and Methods: In this study, 2968 patients with Pyrexia of unknown origin (PUO) were included .Rapid Card test and Enzyme Linked Immunosorbent Assay (ELISA) were used for testing serum of patients.
Results: Of 2968, 521 were clinically suspected cases of dengue. Of 521 patients, 228 were confirmed to have dengue. The prevalence was 7.8% in this study.
Conclusion: Dengue fever continues to be a major public health problem. The study showed that 7.8 % of study population has dengue disease. The study highlights that preventive measures against dengue infection should be taken during the monsoon and post monsoon months.
Keywords: Prevalence, Dengue fever, Mumbai, Pyrexia of unknown origin (PUO).
References
- Dengue in South East Region, 2010. A report by World Health Organization , (Available on WHO website). Accessed February 25, 2010.
- Kumar A, Rao CR, Pandit V, Shetty S, Bammigatti C, and Samarasinghe CM. Clinical manifestations and trend of dengue cases admitted in a tertiary care hospital, Udupi district, Karnataka. Indian J Community Med 2010; 35(3): 386–90.
- Mehendale SM, Risbud AR, Rao JA, Banerjee K. Outbreak of Dengue fever in rural areas of Parbhani district of Maharashtra, India. Indian J Med Res 1991; 93: 6–11.
- Padbidri VS, Mahadev PV, Thakre JP, Pant U, Illkal MA, Varghese GG, et al.,. Virological and entomological investigat-ions of an outbreak of dengue fever in Dhule district, Maharashtra. Indian J Med Microbiology 1996; 14: 25–32.
- Ukey PM, Bondade SA, Paunipagar PV, Powar RM, Akulwar SL. Study of seroprevalence of dengue fever in central India. Indian J Community Med 2010; 35: 517-
- Halstead S.B., Mosquito borne haemorrhagic fever of South and South East Asia. Bull World Health Organization 1966; 35: 3-15.
- Park K. Park’s textbook of preventive and social medicine.21st ed. Jabalpur: Banarasidas Bhanot . 2009 19 : 225-6.
- Guzman MG, Kouri G. Dengue diagnosis, advances and challenges. Int J Infect Dis 2004; 8(2): 69-80.
- WHO (2009). Dengue Haemorrhagic Fever: Diagnosis, Treatment, Prevention and Control
- Gubler DJ. Dengue and dengue hemorrhagic fever. Clin Microbiology Rev 1998; 11:480-96.
- Baruah K, Dhariwal AC. Epidemiology of dengue, its prevention and control in India. J. of Indian Medical Asso 2011;109:2.
- Garg P, Nagpal J, Khairnar P and Seneviratne S L. Economic burden of dengue infections in India; Trans R Soc Trop MedHyg2008;102: 570–7.
- Kumar A, Rao CR, Pandit V, Shetty S, Bammigatti C, and Samarasinghe CM. Clinical manifestations and trend of dengue cases admitted in a tertiary care hospital, Udupi district, Karnataka. Indian J Community Med 2010; 35(3):386–90.
- Kuno G, Gomez I, Gubler DJ. Detecting artificial anti-dengue IgM immune complexes using an enzyme-linked immunosorbent assay. Am J Trop Med Hyg 1987; 36:153-9.
- Amin MMM, Hussain AMZ, Murshed M, Chowdhury AI, Mannan S, Chowdhury SA. Serodiagnosis of dengue infections by haemagglutination inhibition test (HI) in suspected cases in Chittagong, Bangladesh WHO Dengue Bulletin 1999;23:34–8.
- Rebelo JMM, Costa JML, Silva FS, Pereira YNO and Silva JM. Distribution of Aedesaegypti and dengue in the state of Maranhao. In Portuguese. Cad Saude Pub 1999, 15(3): 477-86
- Barrera R, Delgado N, Jimenez M, Valero S: Eco-epidemiological factors associated with hyperendemic dengue hemorrhagic fever in Maracay city, Venezuela. Dengue Bull 2002, 26:84- 95.
Corresponding Author
Shilpi Hora
Contact No. 8769115996, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v6i3.90
