Objectives: To find the incidence of leiomyoma and endometrial lesion as the cause of AUB in women in different age groups.

Materials and Methods: A retrospective study was conducted on 612 of patients presenting with abnormal uterine bleeding over period of five years.

Result: Age of patients ranged from 17 to 79 year. Most commonly encountered in 4^th Decade of life. The commonest pathology irrespective of the age group was disordered proliferative pattern. In my study  among 612 patient undergoing hysterectomy causes were leiomyoma ( 68%),Adenomyosis ( 08 %), Leiomyoma and adenomyosis( 15 %),Endometrial polyp( 3 %) Endometrial hyperplasia (3.1 %) endometrial carcinoma (3.2%).

Discussion: Abnormal uterine bleeding is the most common cause for a women to consult a gyneacologist. Etiology is different for various age groups. Maximum cases of AUB in our study was observed in perimenopausal age group. Leiomyoma is common finding in women with AUB followed by adenomyosis. Cases of endometrial polyp and endometrial carcinoma reported mostly occurs in postmenopausal age group.

Conclusion: In this study leiomyoma was found to be the most common cause for AUB and hysterectomies, followed by adenomyosis in women with peak incidence in the perimenopausal age group.

Keywords: Abnormal uterine bleeding, Leiomyoma, Endometrial lesion.

1. National Institute for Health and Care Excellence .Heavy menstrual bleeding. London, UK: National Institute for Health and Care Excellence; 2007. Clinical guidance 44. Available from: nice.org.uk/guidance/cg44/resources/guidance-heavy-menstrual-bleeding-pdf. Accessed 2015 Jun 18.
2. Merrill R.M. Hysterectomy surveillance in the United States, 1997 through 2005. Med SciMonit. 2008;14:CR24–31. [PubMed]
3. Stewart E.A. Uterine fibroids. Lancet. 2001;357:293–298. [PubMed]
4. Brahma P.K., Martel K.M., Christman G.M. Future directions in myoma research. ObstetGynecolClin North Am. 2006;33:199–224. xiii. [PubMed]
5. Lucy Whitaker et al;Anormal uterine bleeding; Best Pract Res ClinObstetGynaecol. 2016 Jul; 34: 54–65
6. Sukhbir Singh et al Abnormal Uterine Bleeding inPre-Menopausal women; J ObstetGynaecol Can 2013;35(5):473–475
7. Doraiswami S ,Johnson T et al; Study of Endometrial Pathology in Abnormal Uterine Bleeding The Journal of Obstetrics and Gynecology of India (July–August 2011) 61(4):426–430;
8. Brenner PF. Differential diagnosis of AUB. Am J Obstet Gynecol.1996;175:766–9 Yusuf NW, Nadeem R,
9. Yusuf AW, et al. Dysfunctional uterine bleeding. A retrospective clinicopathological study over 2 years.Pak J ObstetGynaecol. 1996;9:27–30.
10. Muzaffar M, Akhtar KAK, Yasmin S, et al. Menstrual irregularities with excessive blood loss: a clinico-pathologic correlation.J Pak Med Assoc. 2005;55:486–9.
11. Escoffery CT, Blake GO, Sargenat LA. Histopathological findings in women with postmenopausal bleeding in Jamaica. West Indian Med J. 2002;51:232–5.
12. Brahma P.K., Martel K.M., Christman G.M. Future directions in myoma research. ObstetGynecolClin North Am. 2006;33:199–224. xiii. [PubMed]
13. Merrill R.M. Hysterectomy surveillance in the United States, 1997 through 2005. Med SciMonit. 2008;14:CR24–31. [PubMed]
14. Stewart E.A. Uterine fibroids. Lancet. 2001;357:293–298. [PubMed]
15. Cardozo E.R., Clark A.D., Banks N.K. The estimated annual cost of uterine leiomyomata in the United States. Am J Obstet Gynecol. 2012;206:211.e1–211.e9. [PubMed]
16. Dreisler E., Stampe Sorensen S., Ibsen P.H. Prevalence of endometrial polyps and abnormal uterine bleeding in a Danish population aged 20-74 years. Ultrasound Obstet Gynecol. 2009;33:102–108. [PubMed]
17. Preutthipan S., Herabutya Y. Hysteroscopic-polypectomy in 240 premenopausal and postmenopausal women. FertilSteril. 2005;83: 705–709. [PubMed]
18. Lieng M., Istre O., Sandvik L. Prevalence, 1-year regression rate, and clinical significance of asymptomatic endometrial polyps: cross-sectional study. J Minim Invasive Gynecol. 2009;16:465–471. [PubMed]
19. Van den Bosch T., Ameye L., Van Schoubroeck D. Intra-cavitary uterine pathology in women with abnormal uterine bleeding: a prospective study of 1220 women. Facts Views Vis Obgyn. 2015;7:17–24. [PubMed]
20. Naftalin J., Hoo W., Pateman K. Is adenomyosis associated with menorrhagia? Hum Reprod. 2014;29:473–479. [PubMed]
21. Hulka C.A., Hall D.A., McCarthy K. Sonographic findings in patients with adenomyosis: can sonography assist in predicting extent of disease? AJR Am J Roentgenol. 2002;179:379–383. [PubMed]

Ghanghoria Shikha