Abstract
Aim: This study was undertaken to identify the age groups, gender distribution and different histopathological types of neoplastic lesions in nephrectomy specimens.
Materials and Methods: This was a retrospective record analysis done over a period of ten years (January 2006 to December 2015). All nephrectomy specimens with a diagnosis of renal tumor, received in the department of Pathology, Government Medical College, Kottayam, Kerala were recorded from histopathology registers and analyzed with regard to age, gender and histopathological types.
Results: A total of 250 renal tumors were encountered. The patients’ age ranged from 2 months to 85 years. Males (66%) were affected more than females (34%) (M: F =1.94:1). Renal tumors were commoner in the 6thand 7th decades. Malignant tumors (90.4%) clearly outnumbered benign tumors (9.6%). Renal cell carcinoma (RCC) was the commonest tumor (71.2%) followed by transitional cell carcinoma (TCC) (10%), oncocytoma (4.4%) and Wilms tumor (WT) (4%). Most common benign tumor was oncocytoma. Wilms tumor was the commonest pediatric tumor.
Conclusions: This retrospective study showed distribution of renal tumors in nephrectomies performed at our institution. The results obtained were comparable with available data from other countries.
Keywords: Renal cell carcinoma, Nephrectomy, Wilms tumor, Oncocytoma, Kerala
References
- Ferlay, J., Soerjomataram, I., Ervik, M. et al. GLOBOCAN 2012v1.0, Cancer Incidence and Mortality Worldwide. IARC Cancer Base No. 11. Lyon, France: International Agency for Research on Cancer. 2013.
- Moch, Amin M.B, Argani P, Cheville J, Delahunt B, Martignoni G.et al. World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs. Lyon: IARC Press; 2016, p.14.
- American Cancer Society. Cancer Facts & Figures; 2017. Atlanta: American Cancer Society; 2017.
- Znaor A, et al. International Variations and Trends in Renal Cell Carcinoma. Eur Urol. 2015; 67:519-30.
- Bashir N, Bashir Y, Shah P, Bhat N, Salim O, Samoon N. Histopathological study of renal tumors in resected nephrectomy specimens - An experience from tertiary care centre. Nat J Med Res. 2015; 5:25-9.
- Rafique M: Nephrectomy: indications, complications and mortality in 154 consecutive patients. J Pak Med Assoc. 2007; 57:308-11.
- Albasri AM, El-Siddig AA, Hussainy AS, Alhujaily AS. Clinicopathologic patterns of adult renal tumors. Saudi J Med Sci. 2017; 5:242-7.
- Latif F, Mubarak M, Kazi JI. Histopathological characteristics of adult renal tumours: a preliminary report. J Pak Med Assoc. 2011; 61: 224-8.
- Dogra PN, Gupta NP, Ishwar R, Kumar A, Seth A. Renal tumors presentation: Changing trends over two decades. Indian J Cancer. 2010; 47: 287-91.
- Kyei MY, Klufio GO, mensah JE, Gyasi RK, Attee SG, Ampadu K. Nephrectomy in adults: Experience at the Korle Bu Teaching Hospital, Accra, Ghana. Saudi J Kidney Dis Transpl 2015; 26: 638-42.
- Mandal KC, Mukhopadhyay M, Barman S, Halder P, Mukhopadhyay B, Kumar R. Uncommon renal tumors in children: A single center experience. J Indian Assoc Pediatr Surg. 2016; 21: 61-5.
Corresponding Author
Dr Sharath K. Krishnan
Department of Surgery, Government Medical College, Thrissur, Kerala, India
Email: sharathkkrishnan@gmail.com