Abstract
Minimal hepatic encephalopathy (MHE) is the earliest form of hepatic encephalopathy and can affect up to 80% of cirrhotic patients. MHE patients have normal mental and neurological status on standard clinical examination but exhibit a number of neuropsychiatric and neurophysiological defects, thus causing difficulty in daily tasks including driving etc.
Aim and objective of study: There are few studies conducted in India related to MHE. Hence the present study was undertaken to determine the prevalence of Minimal Hepatic Encephalopathy.
Material and Methods: 50 adult patients with established liver cirrhosis were studied for neuropsychiatric and neurophysiologic tests.
Results: The prevalence of Minimal Hepatic encephalopathy (MHE) was 30% in the study population.
Conclusions: MHE is an significant disorder that may seriously impair patients’ daily functioning and quality of life. MHE predicts the development of overt hepatic encephalopathy. Inspite of the various tools used, in the absence of a “gold standard,” a combination of test methods is recommended to diagnose MHE most reliably. The key point of emphasis is to identify the patients in presymptomatic stage and intervene early enough in order to halt the morbid and fatal future outcomes in liver cirrhotic patients.
Keywords: MHE (minimal hepatic encephalopathy), neurophysiological and neuropsychiatric tests.
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Corresponding Author
Dr Pankaj H Bansode
Associate Professor in Surgery,
Bharati Vidyapeeth (Deemed to be University) Medical College, Pune
DOI: https://dx.doi.org/10.18535/jmscr/v5i12.138
