Abstract
Introduction: Lung cancer is the most commonly diagnosed cancer worldwide and causes approximately 1–2 million deaths per year. Non-small cell lung cancer (NSCLC) accounts for at least 80% of all lung cancer cases, presenting as locally advanced disease in approximately 25–30% of cases and as metastatic disease in approximately 40–50% of cases.
Aim of the work: The aims & objectives of this study was to study the improvement in Health Related Quality Of Life, treatment related side-effects and overall survival..
Patients and Methods: A prospective clinical study included 60 patients who were randomly assigned into two groups; group (A) 30 patients received RT regimen of 5 fractions of 4 Gy over 2 weeks to a total dose of 30 Gy, and group (B) 30 patients received RT regimen of two fractions of 8.5 Gy days 1 and 8 to a total dose of 17 Gy..
Results: The hypo fractionated RT regimens used in this study proved to be equally effective as the more protracted regimen in terms of treatment tolerance, HRQOL, and overall survival. This may hopefully convince at least some radiation oncologists still using more protracted regimens to adopt this simple and efficient treatment.
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Corresponding Author
Sofi Mushtaq Ahmad
Senior Resident, Department of Radiation Oncology SKIMS Soura Srinagar
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., M.No:09858811647
DOI: https://dx.doi.org/10.18535/jmscr/v5i12.137
