Abstract
Background: Sudden Sensory Neural Hearing Loss (SSNHL) is loss of 30dB HL over three contiguous audiometric frequencies within 3 days and the incidence is 5-20 per 1,00,000 population occurring mostly among adults in fifties and sixties. The cause is idiopathic but recently been attributed to disturbance in cochlear microcirculation secondary to dyslipidaemia.
Aim and Objective: The aim of our study is to establish a relationship between sudden sensory neural hearing loss (SSNHL) and vascular risk factors like serum lipid and uric acid.
Material & Methods: This is a case control study of 40 cases of SSNHL of age group 26-65 years attending the outpatient Department (OPD) of E.N.T, VIMSAR, Burla between 1st September to 30th November, 2017. After patient history, physical examinations and audiological examination, blood parameters like lipid profile and uric acid level were analysed. Levels of total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL-CH), very low density lipoprotein (VLDL-CH), high density lipoprotein (HDL-CH) and uric acid (UA) of these patients then compared with an age and sex matched control group of 40 patients treated in the same OPD for E.N.T diseases other than hearing loss during the same period.
Result: Statistical analysis showed that there was significant difference between the means of lipid profile and uric acid of the patients and the control group.
Conclusion: This study indicates that metabolic disturbances of serum lipids and uric acid may be potential risk factors for SSNHL.
Keywords: Sudden sensory neural hearing loss(SSNHL), dyslipidaemia, uric acid.
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Corresponding Author
Dr Sumitra Bhoi
Assistant Professor, Biochemistry, VIMSAR, Burla, Odisha, India
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Phone no: 919438271740
DOI: https://dx.doi.org/10.18535/jmscr/v5i12.109
