Title: Unusual Presentation of Infiltrating Thymoma in Myesthenia Patient: A Case Report and Review of Literature
Authors: Sonia Agarwal, Mamta Chaudhary, B.P.Nag.
DOI: https://dx.doi.org/10.18535/jmscr/v5i12.42
Abstract
Myasthenia gravis (MG) is associated with multiple variants of invasive thymomas which have been reported in literature. Unfortunately there is no clear histologic distinction exists between benign and malignant thymomas. These cases if not diagnosed properly may present in later stages with a turbulent course and prognosis. Invasive thymomas were correlated with a higher probability of recurrence. Good outcome can be obtained if early and definitive diagnosis of capsular invasion has been made during histopathological examination (HPE). The consensus is that patients with invasive thymoma, should receive neo-adjuvant therapy for better outcome. We encountered a rare type of invasive thymoma in which thymic cells were infiltrating through the capsule into pericapsular adipose tissue. This type of capsular invasion maybe considered potentially curable, if diagnosed early and can guide clinicians in deciding neo-adjuvant therapy after radical surgery.
Keywords: Invasive thymoma, Myasthenia gravis, neo adjuvent therapy.
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