Title: Molecular Cloning and Characterization of Pregnancy Specific Protein Uteroglobin can Lead to Pregnancy Detection in Cattle- A Review
Authors: Er. Nazakat Ali, Dr Manoj Kumar Jena
DOI: https://dx.doi.org/10.18535/jmscr/v5i12.05
Abstract
Various kinds of approaches are treated of early pregnancy diagnosis for further aggravates the situation. Several methods of pregnancy diagnosis are being practiced in bovine species, yet none qualifies as the ideal pregnancy diagnosis method due to the inherent limitations of sensitivity, accuracy, specificity, speed, and ease of performing the test. One concern with previous assessments of this test is that animals with viable embryos early during pregnancy that subsequently undergo embryonic loss before pregnancy diagnosis increase the rate of false-positive results and bias the assessment. Assessment of a Commercially Available Early Conception Factor (ECF) Test for Determining Pregnancy Status of Dairy Cattle, while assessing the usefulness of the modern technologies in detecting novel pregnancy markers and designing future strategies for research in this area. Uteroglobin is a small progesterone-binding protein expressed in various organs of the cattle. Uteroglobin (UG) is an anti-inflammatory protein secreted by the airway epithelia of all mammals. A critical role of UG in preventing the development of PF and the of principle that recombinant UG may have therapeutic potential. The early pregnancy detection can be done by examining different proteins dubbed as pregnancy specific proteins like PAGs, PSPB, Uteroglobin, interferon-induced GTP binding proteins etc.
Keywords: Urine, Biomarker, DIGE, LFQ, Mass spectrometry, Gene Ontology, Network construction, Bovine serum, Plasma, Milk.
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