Abstract
Background: Vascular cognitive impairment (VCI) is poised to become the silent epidemic of the 21st century and contribute significantly to mortality, disability, and decreased quality of life. .
Aim: To investigate the frequency and clinical determinants of vascular dementia (VD) and Vascular mild cognitive impairment (VMCI) following ischemic stroke. The one year follow-up was done to assess the prognosis.
Materials and Methods: A prospective study was conducted among 100 consecutive patients aged ≥40 years with the diagnosis of ischemic stroke within previous 2 - 3 months. The subjects were be subjected to structured medical and neurological history based on review of all available hospital charts, interview of the subject and a knowledgeable informant, and a structured clinical, neurological, neuropsychological, and neuroradiological evaluation. Patients will be retested at 3, 6, and 12 months after stroke. .
Results: 60% of stroke patients were diagnosed as VCI. 23 subjects were diagnosed as VD. The prevalence of VMCI was 37% and forty percent of the patients had no cognitive impairment. An annual conversion rate from ‘VMCI’ to ‘VD was 8%. The annual rate of deterioration from ‘No Cognitive Impairment’ to ‘VMCI’ was 10% .
Conclusion: This study supports the high prevalence of dementia and mild cognitive impairment following stroke, especially in older individuals, and highlights the importance of cognitive reserve. .
Keywords: Ischemic stroke, vascular dementia, Vascular cognitive impairment, Vascular mild cognitive impairment.
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Corresponding Author
Murugapandian Nagarajan
Senior Assistant Professor of Neurology,
Govt. Kilpauk Medical College, Chennai-10, India
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Tel:+91-9443921569
DOI: https://dx.doi.org/10.18535/jmscr/v5i10.180
