Title: Urinary Iodide Excretion Studies in Thyroid Patients in North Kerala

Authors: Minikumari Amma.V., Anu.E.B., P.S.Harikumar, Indu Sasidharan

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i10.175

Abstract

Background: Iodine is a micronutrient for the synthesis of thyroid hormones. The decreased production of thyroid hormone results in hypothyroidism. One of the reasons for hypothyroidism is iodine deficiency. The prevalence of thyroid disease is very high in Kerala even after implementing universal salt iodization. The aim of this study was to find out whether the iodine intake is normal in thyroid patients consuming only non-iodized salt.

Methods: The study was conducted among the thyroid patients attending the Out Patient Departments of Kozhikode Medical College. Through thyroid hormonal assay, well established cases of hypo and hyper thyroid patients were taken under study. 24hr urine samples from 500 thyroid patients and 500 normal controls were collected. 24 hr urinary iodide estimation was done in the CWAL of CWRDM, Kunnamangalam.

Result: The average urinary iodide excretion was found to be 190, 188.2,187.9 and 190 µg/day in hypo, their control, hyper and their control respectively.

Conclusion: Nutritional iodine deficiency is not the major problem as judged by urinary iodide excretion study.

Keywords: Iodine deficiency, urinary iodide, hypothyroidism

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