Abstract
Background: Echocardiography is used to assess cardiac parameters. Altered parameters can affect the morbidity in patients of hypothyroidism so echocardiography can be used to assess morbidity in such cases.
Aims and Objective: To measure cardiac functions in patients of hypothyroidism and to correlate cardiac functions with euthyroid state.
Material and Methods: The study conducted at M.M.I.M.S.R, Mullana. Ambala. Fifty individuals were included in the study out of them 25 were cases and 25 were control. The patients were taken from both from OPD and Indoor wards of department of Medicine. The patients were studied during October 2014 to December 2016. All the patients were scrutinized and investigated as per the plan. All were subjected to evaluation by echocardiography, electrocardiography and x-ray chest.
Results: In our study there was significant increase in left ventricular mass with preserved left ventricular systolic function.
Conclusion: Echocardiography can be used as a sensitive tool to assess morbidity associated with hypothyroidism.
Keywords: Echocardiography, Left ventricular mass, hypothyroidism, euthyroid.
References
- Kahaly GJ, Dillmann WH. Thyroid hormone action in the heart.Endocr Rev. 2005;26(5):704-28.
- Biondi B, Palmieri EA, Lombardi G, Fazio S. Effects of thyroid hormone on cardiac function: the relative importance of heart rate, loading conditions, and myocardial contractility in the regulation of cardiac performance in human hyperthyroidism. J Clin Endocrinol Metab. 2002;87(3):968-74.
- Crowley WF, Jr., Ridgway EC, Bough EW, Francis GS, Daniels GH,Kourides IA, et al. Noninvasive evaluation of cardiac function in hypothyroidism. Response to gradual thyroxine N Engl J Med. 1977;296 (1):1-6.
- Klein I, Danzi S. Thyroid disease and the heart. Circulation 2007;116 (15):1725-35.
- Feigenbaum H. 2-Dimensional measure-ment In: Feigenbaum’s echocardiography Feigenbaum H, Armstron WF, Ryan T, editors. 6th edition; 2005:141-45.
- Samanta BB. Clinical profile of hypothyroidism. Ind Med Gazette 1995-1997.p.7-11.
- Pearce EN, Yang Q, Benjamin EJ, Aragam J, Vasan RS. Thyroid function and left ventricular structure and function in the Framingham Heart Study. Thyroid. 2010;20(4):369-73.
- Velkoska Nakova V, Krstevska B, Bosevski M, Dimitrovski C, Serafimoski Dyslipidaemia and hypertension in patients with subclinical hypothyroidism. Prilozi. 2009;30 (2):93-102.
- Rajasekhar P, SunithaA, VamsiVihari G. Cross Sectional Study of Cadiovascular Manifestations in Hypothyroidism. IJAR. 2015;5 (4):564- 6544.Kotha S.
- Hadzovic-Dzuvo A, Kucukalic-Selimovic E, Nakas-Icindic E, Rasic S, Begic A, Al Tawil D, et al. Echocardiographic evaluation of cardiac function in female patients with thyroid disorders. Bosn J Basic Med Sci. 2010;10(2) :112-15
- Monzani F, Di Bello V, Caraccio N, Bertini A, Giorgi D, Giusti C, et al. Effect of levothyroxine on cardiac function and structure in subclinical hypothyroidism: a double blind, placebo-controlled study. J Clin Endocrinol Metab. 2001;86(3):1110-15
Corresponding Author
Munish Gupta
H.No-1211/11 Ambala Road, Model Town, Kaithal,136027
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.