Title: Clinical Study to Compare the Efficacy of Platelet Rich Plasma versus Conventional Dressing in Chronic Diabetic Non Healing Ulcers
Authors: Dr S.Praveenkumar, Dr J.Kabalimurty, Dr C.Stalinraja
DOI: https://dx.doi.org/10.18535/jmscr/v5i10.153
Abstract
Diabetic non healing ulcers are a frequent of amputation and represent substantial expenses to fitness care and decrease patient best of existence. The purpose of wound management is to attain wound closure as expeditiously as possible. Apart from these conventional methods to facilitate wound numerous new methods are emerging such as cellular therapies like platelet-rich plasma (PRP). Platelets release certain factors from alpha granules which can be placed in thrombocyte cell membrane which include platelet derived growth factor (PDGF), platelet derived angiogenesis factor, epidermal growth factor (EGF), and platelet factor 4. These elements act regionally on wound and promotes the recovery process. This was a prospective study conducted at Rajah Muthiah Medical College, Chidambaram. Total of forty six patients were assigned. They have been grouped into two by computerized randomization. Patients in control group were treated with traditional dressing and patients in study group have been handled with PLATELET RICH PLASMA (PRP) dressing and observed for decrease in the wound size. This have a look at intends to demonstrate the healing function of autologous platelet rich plasma in healing of chronic non-healing diabetic ulcers.
Keywords: Platelet rich plasma, chronic diabetic non healing ulcers.
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